BDBM50028978 1-(2-Chloro-5H-dibenzo[a,d]cyclohepten-10-yl)-4-methyl-piperidine::CHEMBL269396

SMILES CC1CCN(CC1)C1=Cc2cc(Cl)ccc2Cc2ccccc12

InChI Key InChIKey=AENACYRRZFSOSG-UHFFFAOYSA-N

Data  5 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50028978   

Target5-hydroxytryptamine receptor 3A/3B(Rattus norvegicus)
Vanderbilt University

Curated by ChEMBL
LigandPNGBDBM50028978(1-(2-Chloro-5H-dibenzo[a,d]cyclohepten-10-yl)-4-me...)
Affinity DataKi: >1.00E+3nMAssay Description:Affinity of the compound was evaluated as inhibition constant for serotonin 5-hydroxytryptamine 3 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(4) dopamine receptor(Homo sapiens (Human))
Vanderbilt University

Curated by ChEMBL
LigandPNGBDBM50028978(1-(2-Chloro-5H-dibenzo[a,d]cyclohepten-10-yl)-4-me...)
Affinity DataKi:  1.00E+3nMAssay Description:Affinity was evaluated as inhibition constant for dopamine D-4 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A(Rattus norvegicus (rat))
Vanderbilt University

Curated by ChEMBL
LigandPNGBDBM50028978(1-(2-Chloro-5H-dibenzo[a,d]cyclohepten-10-yl)-4-me...)
Affinity DataKi: >1.00E+3nMAssay Description:Affinity was evaluated as inhibition constant for serotonin 5-hydroxytryptamine 2A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2C(Rattus norvegicus (Rat))
Vanderbilt University

Curated by ChEMBL
LigandPNGBDBM50028978(1-(2-Chloro-5H-dibenzo[a,d]cyclohepten-10-yl)-4-me...)
Affinity DataKi: >1.00E+3nMAssay Description:Affinity was evaluated as inhibition constant for serotonin 5-hydroxytryptamine 2C receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Vanderbilt University

Curated by ChEMBL
LigandPNGBDBM50028978(1-(2-Chloro-5H-dibenzo[a,d]cyclohepten-10-yl)-4-me...)
Affinity DataKi:  1.40E+3nMAssay Description:Affinity was evaluated as inhibition constant for dopamine D-2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(1A)/D(1B)/D(2)/D(3)/D(4) dopamine receptor(Rattus norvegicus (rat))
TBA

Curated by ChEMBL
LigandPNGBDBM50028978(1-(2-Chloro-5H-dibenzo[a,d]cyclohepten-10-yl)-4-me...)
Affinity DataIC50: >1.00E+4nMAssay Description:Relative affinity for dopamine receptor by displacement of [3H]spiroperidol (2.2 nM) from (in vitro) dopamine binding sites in rat caudate nucleiMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50028978(1-(2-Chloro-5H-dibenzo[a,d]cyclohepten-10-yl)-4-me...)
Affinity DataIC50: >1.00E+4nMAssay Description:Concentration required (in vitro) to displace 50% specific binding of [3H]clozapine to Muscarinic acetylcholine receptor in rat brainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed