BDBM50029074 2-{1-[(4-chlorophenyl)carbonyl]-5-hydroxy-2-methylindol-3-yl}acetic acid::CHEMBL6::DESMETHYL INDOMETHACIN::[1-(4-Chloro-benzoyl)-5-hydroxy-2-methyl-1H-indol-3-yl]-acetic acid::[1-(4-Chloro-benzoyl)-5-hydroxy-2-methyl-1H-indol-3-yl]-acetic acid( Indomethacin)

SMILES Cc1c(CC(O)=O)c2cc(O)ccc2n1C(=O)c1ccc(Cl)cc1

InChI Key InChIKey=KMLNWQPYFBIALN-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50029074   

TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
Nitromed

Curated by ChEMBL
LigandPNGBDBM50029074(2-{1-[(4-chlorophenyl)carbonyl]-5-hydroxy-2-methyl...)
Affinity DataIC50:  1.56E+4nMAssay Description:Inhibition of COX1 in human whole blood assessed as effect on A23187-induced thromboxane B2 productionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B1 [K65Q](Bos taurus (Cattle))
Sankyo

Curated by ChEMBL
LigandPNGBDBM50029074(2-{1-[(4-chlorophenyl)carbonyl]-5-hydroxy-2-methyl...)
Affinity DataIC50:  3.20E+3nMAssay Description:Inhibition of Aldose reductase (AR)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Nitromed

Curated by ChEMBL
LigandPNGBDBM50029074(2-{1-[(4-chlorophenyl)carbonyl]-5-hydroxy-2-methyl...)
Affinity DataIC50:  5.00E+3nMAssay Description:Inhibition of COX2 in human whole blood assessed as effect on LPS-induced thromboxane B2 productionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedMMDB