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BDBM50029256 1-(5-{2-[4-(2-Methoxy-phenyl)-piperazin-1-yl]-ethyl}-1-methyl-1H-pyrrol-2-yl)-2-piperidin-1-yl-ethane-1,2-dione;succinate

SMILES: COc1ccccc1N1CCN(CCc2ccc(C(=O)C(=O)N3CCCCC3)n2C)CC1

InChI Key: InChIKey=MQEMNNSHSPSDOJ-UHFFFAOYSA-N

Data: 2 KI

Find this compound or compounds like it in BindingDB or PDB:
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50029256   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Serotonin (5-HT) receptor


(Rattus norvegicus (rat))
BDBM50029256
PNG
(1-(5-{2-[4-(2-Methoxy-phenyl)-piperazin-1-yl]-ethy...)
Show SMILES COc1ccccc1N1CCN(CCc2ccc(C(=O)C(=O)N3CCCCC3)n2C)CC1
Show InChI InChI=1S/C25H34N4O3/c1-26-20(10-11-22(26)24(30)25(31)29-13-6-3-7-14-29)12-15-27-16-18-28(19-17-27)21-8-4-5-9-23(21)32-2/h4-5,8-11H,3,6-7,12-19H2,1-2H3
KEGG

GoogleScholar
PC cid
PC sid
UniChem

Similars

Article
PubMed
25n/an/an/an/an/an/an/an/a



R. W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL


Assay Description
Binding affinity was determined against 5-hydroxytryptamine 1A receptor using [3H]WB-4101


J Med Chem 38: 4198-210 (1995)


Article DOI: 10.1021/jm00021a009
BindingDB Entry DOI: 10.7270/Q2GX4C61
More data for this
Ligand-Target Pair
Dopamine D2 receptor/Serotonin 2 (5-HT2) receptor


(Rattus norvegicus (rat))
BDBM50029256
PNG
(1-(5-{2-[4-(2-Methoxy-phenyl)-piperazin-1-yl]-ethy...)
Show SMILES COc1ccccc1N1CCN(CCc2ccc(C(=O)C(=O)N3CCCCC3)n2C)CC1
Show InChI InChI=1S/C25H34N4O3/c1-26-20(10-11-22(26)24(30)25(31)29-13-6-3-7-14-29)12-15-27-16-18-28(19-17-27)21-8-4-5-9-23(21)32-2/h4-5,8-11H,3,6-7,12-19H2,1-2H3
PDB

Reactome pathway
KEGG

GoogleScholar
PC cid
PC sid
UniChem

Similars

Article
PubMed
>1.00E+3n/an/an/an/an/an/an/an/a



R. W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL


Assay Description
Binding affinity was determined against Dopamine receptor D2 using [3H]spiperone


J Med Chem 38: 4198-210 (1995)


Article DOI: 10.1021/jm00021a009
BindingDB Entry DOI: 10.7270/Q2GX4C61
More data for this
Ligand-Target Pair