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BDBM50029295 3-[4-(2-Isopropoxy-phenyl)-piperazin-1-ylmethyl]-benzylamine ; succinate

SMILES: CC(C)Oc1ccccc1N1CCN(Cc2cccc(CN)c2)CC1

InChI Key: InChIKey=GUAUPJNJQVBWRS-UHFFFAOYSA-N

Data: 2 KI

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50029295   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Serotonin (5-HT) receptor


(Rattus norvegicus (rat))
BDBM50029295
PNG
(3-[4-(2-Isopropoxy-phenyl)-piperazin-1-ylmethyl]-b...)
Show SMILES CC(C)Oc1ccccc1N1CCN(Cc2cccc(CN)c2)CC1
Show InChI InChI=1S/C21H29N3O/c1-17(2)25-21-9-4-3-8-20(21)24-12-10-23(11-13-24)16-19-7-5-6-18(14-19)15-22/h3-9,14,17H,10-13,15-16,22H2,1-2H3
KEGG

GoogleScholar
PC cid
PC sid
UniChem

Similars

Article
PubMed
31n/an/an/an/an/an/an/an/a



R.W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL


Assay Description
Affinity against the 5-hydroxytryptamine receptor 1A using [3H]WB-4101.


J Med Chem 38: 4211-22 (1995)


Article DOI: 10.1021/jm00021a010
BindingDB Entry DOI: 10.7270/Q2C53MH2
More data for this
Ligand-Target Pair
Dopamine D2 receptor/Serotonin 2 (5-HT2) receptor


(Rattus norvegicus (rat))
BDBM50029295
PNG
(3-[4-(2-Isopropoxy-phenyl)-piperazin-1-ylmethyl]-b...)
Show SMILES CC(C)Oc1ccccc1N1CCN(Cc2cccc(CN)c2)CC1
Show InChI InChI=1S/C21H29N3O/c1-17(2)25-21-9-4-3-8-20(21)24-12-10-23(11-13-24)16-19-7-5-6-18(14-19)15-22/h3-9,14,17H,10-13,15-16,22H2,1-2H3
Reactome pathway
KEGG

GoogleScholar
PC cid
PC sid
UniChem

Similars

Article
PubMed
32n/an/an/an/an/an/an/an/a



R.W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL


Assay Description
Binding affinity was determined against Dopamine receptor D2 using [3H]spiperone


J Med Chem 38: 4211-22 (1995)


Article DOI: 10.1021/jm00021a010
BindingDB Entry DOI: 10.7270/Q2C53MH2
More data for this
Ligand-Target Pair