BDBM50029355 3-[(2S,5R,8S,11R,14S)-8-((S)-sec-Butyl)-14-(1H-indol-3-ylmethyl)-11-isobutyl-5-methyl-3,6,9,12,15-pentaoxo-1,4,7,10,13pentaaza-cyclopentadec-2-yl]-propionic acid::CHEMBL343379

SMILES CC[C@H](C)[C@@H]1NC(=O)[C@@H](C)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@@H](CC(C)C)NC1=O

InChI Key InChIKey=UMKHUVRCCMAOBN-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50029355   

TargetEndothelin-1 receptor(Human)
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50029355(3-[(2S,5R,8S,11R,14S)-8-((S)-sec-Butyl)-14-(1H-ind...)
Affinity DataIC50: 590nMAssay Description:Inhibitory effect against Human Endothelin A receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEndothelin-1 receptor(Pig)
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50029355(3-[(2S,5R,8S,11R,14S)-8-((S)-sec-Butyl)-14-(1H-ind...)
Affinity DataIC50: 1.40E+3nMAssay Description:Inhibitory effect against porcine Endothelin A receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEndothelin-1 receptor(Pig)
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50029355(3-[(2S,5R,8S,11R,14S)-8-((S)-sec-Butyl)-14-(1H-ind...)
Affinity DataIC50: 1.40E+3nMAssay Description:The compound was tested for binding inhibitory activity against Endothelin A receptor from porcine aortic smooth muscle membranes.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEndothelin receptor type B(Human)
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50029355(3-[(2S,5R,8S,11R,14S)-8-((S)-sec-Butyl)-14-(1H-ind...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibitory effect against Human Endothelin B receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEndothelin receptor type B(Pig)
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50029355(3-[(2S,5R,8S,11R,14S)-8-((S)-sec-Butyl)-14-(1H-ind...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibitory effect against porcine Endothelin B receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed