BDBM50029431 CHEMBL277293::Dimethyl-(4-phenyl-4H-benzo[b]pyrrolo[1,2-d][1,4]thiazin-1-ylmethyl)-amine

SMILES CN(C)Cc1ccc2C(Sc3ccccc3-n12)c1ccccc1

InChI Key InChIKey=FDBYIIBXPLWFTK-UHFFFAOYSA-N

Data  1 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50029431   

LigandPNGBDBM50029431(CHEMBL277293 | Dimethyl-(4-phenyl-4H-benzo[b]pyrro...)
Affinity DataKi:  118nMAssay Description:Displacement of [3H]nitrendipine from calcium channel receptorMore data for this Ligand-Target Pair
In DepthDetails
TargetVoltage-dependent L-type calcium channel subunit alpha-1D(Rattus norvegicus)
Universita' Degli Studi Di Siena

Curated by ChEMBL
LigandPNGBDBM50029431(CHEMBL277293 | Dimethyl-(4-phenyl-4H-benzo[b]pyrro...)
Affinity DataIC50:  316nMAssay Description:Inhibition of [3H]nitrendipine binding to L-type [Ca2+] channel in rat cortex homogenate, activity expressed as pIC50More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50029431(CHEMBL277293 | Dimethyl-(4-phenyl-4H-benzo[b]pyrro...)
Affinity DataIC50:  315nMAssay Description:Displacement of [3H]nitrendipine from calcium channel receptorMore data for this Ligand-Target Pair
In DepthDetails