BDBM50030145 CHEMBL290701::bis-(1N-[4-cyclopropylmethyl-10-hydroxy-14-oxo-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7,9,11(18)-trien-17-yl]-2-sulfanylacetamide)

SMILES Oc1ccc2C[C@H]3N(CC4CC4)CC[C@@]45[C@@H](Oc1c24)C(=O)CC[C@@]35NC(=O)CSSCC(=O)N[C@]12CCC(=O)[C@@H]3Oc4c5c(C[C@H]1N(CC1CC1)CC[C@@]235)ccc4O

InChI Key InChIKey=CYNYZGWJRWHWPG-CTHHFRLWSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50030145   

TargetDelta-type opioid receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50030145(CHEMBL290701 | bis-(1N-[4-cyclopropylmethyl-10-hyd...)
Affinity DataIC50:  24nMAssay Description:Inhibitory activity of the compound against Opioid receptor delta 1 binding to bovine striatal membraneMore data for this Ligand-Target Pair
In DepthDetails Article
TargetKappa-type opioid receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50030145(CHEMBL290701 | bis-(1N-[4-cyclopropylmethyl-10-hyd...)
Affinity DataIC50:  10nMAssay Description:Inhibitory activity of the compound against Opioid receptor kappa1 binding to bovine striatal membraneMore data for this Ligand-Target Pair
In DepthDetails Article
TargetKappa-type opioid receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50030145(CHEMBL290701 | bis-(1N-[4-cyclopropylmethyl-10-hyd...)
Affinity DataIC50:  10nMAssay Description:Evaluation for the inhibition of kappa opioid binding to bovine striatal membranes by the affinity ligand 1 nM [3H]U-69593 radiolabeled opioidMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50030145(CHEMBL290701 | bis-(1N-[4-cyclopropylmethyl-10-hyd...)
Affinity DataIC50:  24nMAssay Description:Evaluation for the inhibition of delta opioid binding to bovine striatal membranes by the affinity ligand 0.2 nM [3H]-p-Cl-DPDPE radiolabeled opioidMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(CALF)
Institute

Curated by ChEMBL
LigandPNGBDBM50030145(CHEMBL290701 | bis-(1N-[4-cyclopropylmethyl-10-hyd...)
Affinity DataIC50:  3.30nMAssay Description:Evaluation for the inhibition of mu opioid binding to bovine striatal membranes by the affinity ligand 0.25 nM [3H]DAMGO radiolabeled opioidMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(CALF)
Institute

Curated by ChEMBL
LigandPNGBDBM50030145(CHEMBL290701 | bis-(1N-[4-cyclopropylmethyl-10-hyd...)
Affinity DataIC50:  3.90nMAssay Description:Inhibitory activity of the compound against Opioid receptor mu 1 binding to bovine striatal membraneMore data for this Ligand-Target Pair
In DepthDetails Article