BDBM50030605 CHEMBL326889::N-(3,5-Bis-trifluoromethyl-benzyl)-N-methyl-2-(2-methyl-1-oxo-4-phenyl-1,2-dihydro-isoquinolin-3-yl)-acetamide

SMILES CN(Cc1cc(cc(c1)C(F)(F)F)C(F)(F)F)C(=O)Cc1c(-c2ccccc2)c2ccccc2c(=O)n1C

InChI Key InChIKey=SLAOVGOAOZJZKV-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50030605   

TargetSubstance-P receptor(Homo sapiens (Human))
Takeda Chemical Industries

Curated by ChEMBL
LigandPNGBDBM50030605(CHEMBL326889 | N-(3,5-Bis-trifluoromethyl-benzyl)-...)
Affinity DataIC50:  68nMAssay Description:Inhibition of [125I]-BH-Substance P binding to tachykinin receptor 1 in human IM-9 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed