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BDBM50030795 CHEMBL3342398

SMILES: Brc1ccc(cc1)-c1csc2ncc(CNC(=O)Nc3ccc4OCOc4c3)n12

InChI Key: InChIKey=KGZIOSIWUGENOH-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50030795   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Indoleamine 2,3-dioxygenase


(Homo sapiens (Human))
BDBM50030795
PNG
(CHEMBL3342398)
Show SMILES Brc1ccc(cc1)-c1csc2ncc(CNC(=O)Nc3ccc4OCOc4c3)n12
Show InChI InChI=1S/C20H15BrN4O3S/c21-13-3-1-12(2-4-13)16-10-29-20-23-9-15(25(16)20)8-22-19(26)24-14-5-6-17-18(7-14)28-11-27-17/h1-7,9-10H,8,11H2,(H2,22,24,26)
PDB
MMDB

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Similars

Article
PubMed
n/an/a 120n/an/an/an/an/an/a



Dainippon Sumitomo Pharma Co., Ltd

Curated by ChEMBL


Assay Description
Inhibition of human IDO1 assessed as reduction in convertion of N-formylkynurenine to kynurenine incubated for 30 mins


ACS Med Chem Lett 5: 1119-23 (2014)


Article DOI: 10.1021/ml500247w
BindingDB Entry DOI: 10.7270/Q2GM88W5
More data for this
Ligand-Target Pair