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BDBM50030992 5-(3-Isopropoxy-benzyl)-1H-pyrimidine-2,4-dione::CHEMBL127209

SMILES: CC(C)Oc1cccc(Cc2c[nH]c(=O)[nH]c2=O)c1

InChI Key: InChIKey=DIMYXXIOIWXKSG-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50030992   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Uridine phosphorylase 1


(Mus musculus)
BDBM50030992
PNG
(5-(3-Isopropoxy-benzyl)-1H-pyrimidine-2,4-dione | ...)
Show SMILES CC(C)Oc1cccc(Cc2c[nH]c(=O)[nH]c2=O)c1
Show InChI InChI=1S/C14H16N2O3/c1-9(2)19-12-5-3-4-10(7-12)6-11-8-15-14(18)16-13(11)17/h3-5,7-9H,6H2,1-2H3,(H2,15,16,17,18)
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UniProtKB/SwissProt
UniProtKB/TrEMBL

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CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 2.00E+3n/an/an/an/an/an/a



Burroughs Wellcome Co.

Curated by ChEMBL


Assay Description
Inhibition of uridine phosphorylase (UrdPase) from murine liver.


J Med Chem 38: 3850-6 (1995)


Article DOI: 10.1021/jm00019a015
BindingDB Entry DOI: 10.7270/Q2B27T91
More data for this
Ligand-Target Pair