BDBM50031299 6-(2,3-Dichloro-phenyl)-[1,2,4]triazine-3,5-diamine::6-(2,3-Dichloro-phenyl)-[1,2,4]triazine-3,5-diamine(lamotrigine)::6-(2,3-dichlorophenyl)-1,2,4-triazine-3,5-diamine::BW-430C::CHEMBL741::LAMOTRIGINE::Lamictal::Lamictal cd

SMILES: Nc1nnc(c(N)n1)-c1cccc(Cl)c1Cl

InChI Key: InChIKey=PYZRQGJRPPTADH-UHFFFAOYSA-N

Data: 2 KI  26 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 28 hits for monomerid = 50031299   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Potassium voltage-gated channel subfamily H member 2 (Human)	BDBM50031299 (CHEMBL741 | BW-430C | 6-(2,3-Dichloro-phenyl)-[1,2...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.29E+5	n/a	n/a	n/a	n/a	n/a	n/a
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Sodium channel protein type 1/2/3 subunit alpha (Rat)	BDBM50031299 (CHEMBL741 | BW-430C | 6-(2,3-Dichloro-phenyl)-[1,2...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3.10E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Sodium channel protein type 9 subunit alpha (Human)	BDBM50031299 (CHEMBL741 | BW-430C | 6-(2,3-Dichloro-phenyl)-[1,2...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.70E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Sodium channel protein type 3 subunit alpha (Human)	BDBM50031299 (CHEMBL741 | BW-430C | 6-(2,3-Dichloro-phenyl)-[1,2...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.70E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Sodium channel protein type 2 subunit alpha (Human)	BDBM50031299 (CHEMBL741 | BW-430C | 6-(2,3-Dichloro-phenyl)-[1,2...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.70E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Sodium channel protein type 10 subunit alpha (Human)	BDBM50031299 (CHEMBL741 | BW-430C | 6-(2,3-Dichloro-phenyl)-[1,2...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	9.80E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Voltage-dependent L-type calcium channel subunit alpha-1C (Human)	BDBM50031299 (CHEMBL741 | BW-430C | 6-(2,3-Dichloro-phenyl)-[1,2...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.26E+6	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily H member 2 (Human)	BDBM50031299 (CHEMBL741 | BW-430C | 6-(2,3-Dichloro-phenyl)-[1,2...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.51E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
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Sodium channel protein type 5 subunit alpha (Human)	BDBM50031299 (CHEMBL741 | BW-430C | 6-(2,3-Dichloro-phenyl)-[1,2...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily H member 2 (Human)	BDBM50031299 (CHEMBL741 | BW-430C | 6-(2,3-Dichloro-phenyl)-[1,2...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.51E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily H member 2 (Human)	BDBM50031299 (CHEMBL741 | BW-430C | 6-(2,3-Dichloro-phenyl)-[1,2...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3.98E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Sodium channel protein type 5 subunit alpha (Human)	BDBM50031299 (CHEMBL741 | BW-430C | 6-(2,3-Dichloro-phenyl)-[1,2...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3.98E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Voltage-dependent L-type calcium channel subunit alpha-1C (Human)	BDBM50031299 (CHEMBL741 | BW-430C | 6-(2,3-Dichloro-phenyl)-[1,2...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.58E+6	n/a	n/a	n/a	n/a	n/a	n/a
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Potassium voltage-gated channel subfamily E/KQT member 1 (Human)	BDBM50031299 (CHEMBL741 | BW-430C | 6-(2,3-Dichloro-phenyl)-[1,2...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.58E+5	n/a	n/a	n/a	n/a	n/a	n/a
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Bile salt export pump (Human)	BDBM50031299 (CHEMBL741 | BW-430C | 6-(2,3-Dichloro-phenyl)-[1,2...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.33E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Sodium channel protein type 2 subunit alpha (Rat)	BDBM50031299 (CHEMBL741 | BW-430C | 6-(2,3-Dichloro-phenyl)-[1,2...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
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Sigma non-opioid intracellular receptor 1 (Rat)	BDBM50031299 (CHEMBL741 | BW-430C | 6-(2,3-Dichloro-phenyl)-[1,2...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Sodium channel protein type 1/2/3 subunit alpha (Rat)	BDBM50031299 (CHEMBL741 | BW-430C | 6-(2,3-Dichloro-phenyl)-[1,2...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Sodium channel protein type 1/2/3 subunit alpha (Rat)	BDBM50031299 (CHEMBL741 | BW-430C | 6-(2,3-Dichloro-phenyl)-[1,2...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.86E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Sodium channel protein type 2 subunit alpha (Human)	BDBM50031299 (CHEMBL741 | BW-430C | 6-(2,3-Dichloro-phenyl)-[1,2...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Sodium channel protein type 5 subunit alpha (Human)	BDBM50031299 (CHEMBL741 | BW-430C | 6-(2,3-Dichloro-phenyl)-[1,2...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	6.20E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Sodium channel protein type 2 subunit alpha (Human)	BDBM50031299 (CHEMBL741 | BW-430C | 6-(2,3-Dichloro-phenyl)-[1,2...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Sodium channel protein type 10 subunit alpha (Human)	BDBM50031299 (CHEMBL741 | BW-430C | 6-(2,3-Dichloro-phenyl)-[1,2...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	9.60E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Sodium channel protein type 10 subunit alpha (Rat)	BDBM50031299 (CHEMBL741 | BW-430C | 6-(2,3-Dichloro-phenyl)-[1,2...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
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Dihydrofolate reductase (Escherichia coli)	BDBM50031299 (CHEMBL741 | BW-430C | 6-(2,3-Dichloro-phenyl)-[1,2...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3.49E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Sodium channel protein type 1/2/3 subunit alpha (Rat)	BDBM50031299 (CHEMBL741 | BW-430C | 6-(2,3-Dichloro-phenyl)-[1,2...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.14E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Dihydrofolate reductase (Escherichia coli)	BDBM50031299 (CHEMBL741 | BW-430C | 6-(2,3-Dichloro-phenyl)-[1,2...) Show SMILES Show InChI	GoogleScholar	UniChem		1.52E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
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Sodium channel protein type 4 subunit alpha (Human)	BDBM50031299 (CHEMBL741 | BW-430C | 6-(2,3-Dichloro-phenyl)-[1,2...) Show SMILES Show InChI	GoogleScholar	UniChem		1.70E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair