BDBM50031481 (2R,3R,4R,5R)-2,5-Bis-hydroxymethyl-pyrrolidine-3,4-diol::2(R),5(R)-bis(hydroxymethyl)-3(R),4(R)-dihydroxypyrrolidine::2R,5R-dihydroxymethyl-3R,4R-dihydroxypyrrolidine::CHEMBL312653

SMILES: C([C@@H]1[C@H]([C@@H]([C@H](N1)CO)O)O)O

InChI Key: InChIKey=PFYHYHZGDNWFIF-UHFFFAOYSA-N

Data: 18 IC50

PDB links: 1 PDB ID matches this monomer.

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 18 hits for monomerid = 50031481   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Lysosomal alpha-glucosidase (Rat)	BDBM50031481 (2(R),5(R)-bis(hydroxymethyl)-3(R),4(R)-dihydroxypy...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.90E+5	n/a	n/a	n/a	n/a	n/a	n/a
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Sucrase-isomaltase, intestinal (Rat)	BDBM50031481 (2(R),5(R)-bis(hydroxymethyl)-3(R),4(R)-dihydroxypy...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	9.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Glycogen debranching enzyme (Human)	BDBM50031481 (2(R),5(R)-bis(hydroxymethyl)-3(R),4(R)-dihydroxypy...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	9.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Sucrase-isomaltase, intestinal (Rat)	BDBM50031481 (2(R),5(R)-bis(hydroxymethyl)-3(R),4(R)-dihydroxypy...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	6.40E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Sucrase-isomaltase, intestinal (Rat)	BDBM50031481 (2(R),5(R)-bis(hydroxymethyl)-3(R),4(R)-dihydroxypy...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.90E+5	n/a	n/a	n/a	n/a	n/a	n/a
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Alpha-glucosidase MAL62 (Baker's yeast)	BDBM50031481 (2(R),5(R)-bis(hydroxymethyl)-3(R),4(R)-dihydroxypy...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Lactase/phlorizin hydrolase (Rat)	BDBM50031481 (2(R),5(R)-bis(hydroxymethyl)-3(R),4(R)-dihydroxypy...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Lysosomal alpha-glucosidase (Rat)	BDBM50031481 (2(R),5(R)-bis(hydroxymethyl)-3(R),4(R)-dihydroxypy...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	9.20E+4	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Sucrase-isomaltase, intestinal (Rat)	BDBM50031481 (2(R),5(R)-bis(hydroxymethyl)-3(R),4(R)-dihydroxypy...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	9.10E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Sucrase-isomaltase, intestinal (Rat)	BDBM50031481 (2(R),5(R)-bis(hydroxymethyl)-3(R),4(R)-dihydroxypy...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	4.40E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Lysosomal acid glucosylceramidase (Human)	BDBM50031481 (2(R),5(R)-bis(hydroxymethyl)-3(R),4(R)-dihydroxypy...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.71E+5	n/a	n/a	n/a	n/a	n/a	n/a
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Alpha-mannosidase (Rat)	BDBM50031481 (2(R),5(R)-bis(hydroxymethyl)-3(R),4(R)-dihydroxypy...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	<5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Alpha-mannosidase 2 (Rat)	BDBM50031481 (2(R),5(R)-bis(hydroxymethyl)-3(R),4(R)-dihydroxypy...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	<5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Trehalase (Rat)	BDBM50031481 (2(R),5(R)-bis(hydroxymethyl)-3(R),4(R)-dihydroxypy...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3.60E+5	n/a	n/a	n/a	n/a	n/a	n/a
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Maltase-glucoamylase (Human)	BDBM50031481 (2(R),5(R)-bis(hydroxymethyl)-3(R),4(R)-dihydroxypy...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	<5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Lactase/phlorizin hydrolase (Rat)	BDBM50031481 (2(R),5(R)-bis(hydroxymethyl)-3(R),4(R)-dihydroxypy...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Alpha-mannosidase 2C1 (Rat)	BDBM50031481 (2(R),5(R)-bis(hydroxymethyl)-3(R),4(R)-dihydroxypy...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.60E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Sucrase-isomaltase, intestinal (Rat)	BDBM50031481 (2(R),5(R)-bis(hydroxymethyl)-3(R),4(R)-dihydroxypy...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	4.40E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair