BDBM50031666 (10R,13S)-10,13-Dimethyl-17-pyridin-3-yl-1,2,6,7,8,9,10,11,12,13,14,15-dodecahydro-cyclopenta[a]phenanthren-3-one::CHEMBL432751

SMILES C[C@]12CCC3C(CCC4=CC(=O)CC[C@]34C)C1CC=C2c1cccnc1

InChI Key InChIKey=GYJZZAJJENTSTP-VYAPPMEMSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50031666   

TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Homo sapiens (Human))
Institute Of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50031666((10R,13S)-10,13-Dimethyl-17-pyridin-3-yl-1,2,6,7,8...)
Affinity DataIC50:  2.10nMAssay Description:Ability to inhibit the C17,20-lyase enzyme by 50% using 17-alpha-hydroxyprogesterone as substrate.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Homo sapiens (Human))
Institute Of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50031666((10R,13S)-10,13-Dimethyl-17-pyridin-3-yl-1,2,6,7,8...)
Affinity DataIC50:  3nMAssay Description:Inhibition of human progesterone 17-alpha-hydroxylase.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
Institute Of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50031666((10R,13S)-10,13-Dimethyl-17-pyridin-3-yl-1,2,6,7,8...)
Affinity DataIC50:  1.80E+3nMAssay Description:Inhibition of Cytochrome P450 19A1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Homo sapiens (Human))
Institute Of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50031666((10R,13S)-10,13-Dimethyl-17-pyridin-3-yl-1,2,6,7,8...)
Affinity DataIC50:  2.80nMAssay Description:Ability to inhibit the Steroid 17-alpha-hydroxylase/17,20 lyase enzyme by 50%.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed