BDBM50031709 4-Guanidino-benzoic acid 4-carboxymethyl-phenyl ester; compound with methanesulfonic acid::CHEMBL433135

SMILES [#7]\[#6](-[#7])=[#7]/c1ccc(cc1)-[#6](=O)-[#8]-c1ccc(-[#6]-[#6](-[#8])=O)cc1

InChI Key InChIKey=XTKGXPFBKPYFDW-UHFFFAOYSA-N

Data  8 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50031709   

TargetKallikrein-1(Homo sapiens (Human))
Minase Research Institute

Curated by ChEMBL
LigandPNGBDBM50031709(4-Guanidino-benzoic acid 4-carboxymethyl-phenyl es...)
Affinity DataIC50: >1.00E+5nMAssay Description:Concentration required to inhibit enzymatic cleavage of the chromogenic substrate (H-D-Val-Leu-Arg-pNA) for pancreatic kallikrein in vitro.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKallikrein-1(Homo sapiens (Human))
Minase Research Institute

Curated by ChEMBL
LigandPNGBDBM50031709(4-Guanidino-benzoic acid 4-carboxymethyl-phenyl es...)
Affinity DataIC50:  2.32E+3nMAssay Description:Concentration required to inhibit enzymatic cleavage of the chromogenic substrate (H-D-Pro-Phe-Arg-pNA) for plasma kallikrein in vitro.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Minase Research Institute

Curated by ChEMBL
LigandPNGBDBM50031709(4-Guanidino-benzoic acid 4-carboxymethyl-phenyl es...)
Affinity DataIC50:  1.08E+5nMAssay Description:Concentration required to inhibit enzymatic cleavage of the chromogenic substrate (H-D-Phe-Pip-Arg-pNA) thrombin in vitro.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutrophil elastase(Homo sapiens (Human))
Minase Research Institute

Curated by ChEMBL
LigandPNGBDBM50031709(4-Guanidino-benzoic acid 4-carboxymethyl-phenyl es...)
Affinity DataIC50: >1.00E+5nMAssay Description:Concentration required to inhibit enzymatic cleavage of the chromogenic substrate (MeO-Suc-Ala-Ala-Pro-Val-pNA) for sputum elastase in vitro.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetChymotrypsinogen A(Bos taurus (bovine))
Minase Research Institute

Curated by ChEMBL
LigandPNGBDBM50031709(4-Guanidino-benzoic acid 4-carboxymethyl-phenyl es...)
Affinity DataIC50: >1.00E+5nMAssay Description:Concentration required to inhibit enzymatic cleavage of the chromogenic substrate (Suc-Ala-Ala-Pro-Phe-pNA) for chymotrypsin in vitro.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasminogen(Rattus norvegicus)
Minase Research Institute

Curated by ChEMBL
LigandPNGBDBM50031709(4-Guanidino-benzoic acid 4-carboxymethyl-phenyl es...)
Affinity DataIC50:  1.25E+4nMAssay Description:Concentration required to inhibit enzymatic cleavage of the chromogenic substrate (H-D-Val-Leu-Lys-pNA) for plasmin in vitro.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine protease 1(Homo sapiens (Human))
Minase Research Institute

Curated by ChEMBL
LigandPNGBDBM50031709(4-Guanidino-benzoic acid 4-carboxymethyl-phenyl es...)
Affinity DataIC50:  55nMAssay Description:Concentration required to inhibit enzymatic cleavage of the chromogenic substrate (Boc-Phe-Ser-Arg-AMC) for trypsin in vitro.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin G(Homo sapiens (Human))
Minase Research Institute

Curated by ChEMBL
LigandPNGBDBM50031709(4-Guanidino-benzoic acid 4-carboxymethyl-phenyl es...)
Affinity DataIC50: >1.00E+5nMAssay Description:Concentration required to inhibit enzymatic cleavage of the chromogenic substrate (MeO-Suc-Ala-Ala-Pro-Met-pNA) for cathepsin G in vitro.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed