BDBM50031866 6-(((3-chlorophenyl)(methyl)amino)methyl)pyrido[3,2-d]pyrimidine-2,4-diamine::6-{[(3-Chloro-phenyl)-methyl-amino]-methyl}-pyrido[3,2-d]pyrimidine-2,4-diamine::CHEMBL54399

SMILES CN(Cc1ccc2nc(N)nc(N)c2n1)c1cccc(Cl)c1

InChI Key InChIKey=YGMFWJRAPSYNFQ-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50031866   

TargetDihydrofolate reductase(Pneumocystis carinii)
Institute

Curated by ChEMBL
LigandPNGBDBM50031866(6-(((3-chlorophenyl)(methyl)amino)methyl)pyrido[3,...)
Affinity DataIC50:  2.10E+3nMAssay Description:Concentration inhibiting P. carinii dihydrofolate reductaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Institute

Curated by ChEMBL
LigandPNGBDBM50031866(6-(((3-chlorophenyl)(methyl)amino)methyl)pyrido[3,...)
Affinity DataIC50:  20nMAssay Description:Concentration inhibiting T. gondii dihydrofolate reductaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Rattus norvegicus (rat))
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50031866(6-(((3-chlorophenyl)(methyl)amino)methyl)pyrido[3,...)
Affinity DataIC50:  67nMAssay Description:Inhibitory activity against rat liver dihydrofolate reductase.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Saccharomyces cerevisiae)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50031866(6-(((3-chlorophenyl)(methyl)amino)methyl)pyrido[3,...)
Affinity DataIC50:  2.10E+3nMAssay Description:Inhibitory activity against Pneumocystis carinii dihydrofolate reductase.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Institute

Curated by ChEMBL
LigandPNGBDBM50031866(6-(((3-chlorophenyl)(methyl)amino)methyl)pyrido[3,...)
Affinity DataIC50:  20nMAssay Description:Inhibitory activity against Toxoplasma gondii dihydrofolate reductase.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Rattus norvegicus (rat))
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50031866(6-(((3-chlorophenyl)(methyl)amino)methyl)pyrido[3,...)
Affinity DataIC50:  67nMAssay Description:Concentration inhibiting rat liver dihydrofolate reductase .More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed