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BDBM50031963 2,6-Dimethyl-4-[5-oxo-11-(1H-tetrazol-5-yl)-5H-dibenzo[a,d]cyclohepten-3-ylmethoxy]-nicotinic acid ethyl ester::CHEMBL330109

SMILES: CCOC(=O)c1c(C)nc(C)cc1OCc1ccc2c(cc3ccccc3c(=O)c2c1)-c1nnn[nH]1

InChI Key: InChIKey=UOBIGGUJOJQKKI-UHFFFAOYSA-N

Data: 1 KI

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50031963   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Angiotensin II receptor


(Homo sapiens (Human))
BDBM50031963
PNG
(2,6-Dimethyl-4-[5-oxo-11-(1H-tetrazol-5-yl)-5H-dib...)
Show SMILES CCOC(=O)c1c(C)nc(C)cc1OCc1ccc2c(cc3ccccc3c(=O)c2c1)-c1nnn[nH]1
Show InChI InChI=1S/C27H23N5O4/c1-4-35-27(34)24-16(3)28-15(2)11-23(24)36-14-17-9-10-20-21(12-17)25(33)19-8-6-5-7-18(19)13-22(20)26-29-31-32-30-26/h5-13H,4,14H2,1-3H3,(H,29,30,31,32)
PDB

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PC cid
PC sid
UniChem
Article
PubMed
4.30n/an/an/an/an/an/an/an/a



Shionogi & Co., Ltd.

Curated by ChEMBL


Assay Description
Ability to displace [125I]-AII binding to COS cells transfected with a cDNA encoding human Angiotensin II receptor, type 1


J Med Chem 38: 2728-41 (1995)


Article DOI: 10.1021/jm00014a024
BindingDB Entry DOI: 10.7270/Q23B5Z5Q
More data for this
Ligand-Target Pair