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BDBM50032093 CHEMBL96456::N*2*-(4-Fluoro-2-methyl-phenyl)-N*4*-methyl-N*4*-phenyl-thieno[2,3-d]pyrimidine-2,4-diamine

SMILES: CN(c1ccccc1)c1nc(Nc2ccc(F)cc2C)nc2sccc12

InChI Key: InChIKey=IJWMABWJZIUTFU-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50032093   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Potassium-transporting ATPase


(Sus scrofa (Pig))
BDBM50032093
PNG
(CHEMBL96456 | N*2*-(4-Fluoro-2-methyl-phenyl)-N*4*...)
Show SMILES CN(c1ccccc1)c1nc(Nc2ccc(F)cc2C)nc2sccc12
Show InChI InChI=1S/C20H17FN4S/c1-13-12-14(21)8-9-17(13)22-20-23-18(16-10-11-26-19(16)24-20)25(2)15-6-4-3-5-7-15/h3-12H,1-2H3,(H,22,23,24)
PDB

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PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
n/an/a 130n/an/an/an/an/an/a



SmithKline Beecham Pharmaceuticals R&D

Curated by ChEMBL


Assay Description
Inhibition of K+ stimulated gastric ATPase activity


J Med Chem 38: 2763-73 (1995)


Article DOI: 10.1021/jm00014a027
BindingDB Entry DOI: 10.7270/Q2TT4Q0J
More data for this
Ligand-Target Pair