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BDBM50032127 (8-Methoxy-2-pyrrolidin-1-yl-quinazolin-4-yl)-o-tolyl-amine::CHEMBL446158

SMILES: COc1cccc2c(Nc3ccccc3C)nc(nc12)N1CCCC1

InChI Key: InChIKey=YIVCMZPBEDBODU-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50032127   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Potassium-transporting ATPase


(Sus scrofa (Pig))
BDBM50032127
PNG
((8-Methoxy-2-pyrrolidin-1-yl-quinazolin-4-yl)-o-to...)
Show SMILES COc1cccc2c(Nc3ccccc3C)nc(nc12)N1CCCC1
Show InChI InChI=1S/C20H22N4O/c1-14-8-3-4-10-16(14)21-19-15-9-7-11-17(25-2)18(15)22-20(23-19)24-12-5-6-13-24/h3-4,7-11H,5-6,12-13H2,1-2H3,(H,21,22,23)
PDB

UniProtKB/SwissProt

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CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
n/an/a 3.00E+4n/an/an/an/an/an/a



SmithKline Beecham Pharmaceuticals R & D

Curated by ChEMBL


Assay Description
Inhibition of K+ stimulated gastric ATPase activity


J Med Chem 38: 2763-73 (1995)


Article DOI: 10.1021/jm00014a027
BindingDB Entry DOI: 10.7270/Q2TT4Q0J
More data for this
Ligand-Target Pair