BDBM50032172 (S)-3-[(S)-2-((S)-2-Acetylamino-3,3-diphenyl-propionylamino)-4-methyl-pentanoylamino]-N-((1S,2S)-1-{(1S,2S)-1-[(S)-1-carboxy-2-(1H-indol-3-yl)-ethylcarbamoyl]-2-methyl-butylcarbamoyl}-2-methyl-butyl)-succinamic acid::CHEMBL328942
SMILES CC[C@H](C)[C@H](NC(=O)[C@@H](NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](NC(C)=O)C(c1ccccc1)c1ccccc1)[C@@H](C)CC)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(O)=O
InChI Key InChIKey=XUMJJSAQQCTKAO-SRYIDKSASA-N
Data 11 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 11 hits for monomerid = 50032172
Affinity DataIC50: 60nMAssay Description:Binding affinity against endothelin B receptor from rabbit renal vascular smooth musclesMore data for this Ligand-Target Pair
Affinity DataIC50: 70nMAssay Description:Inhibition of ET-1 stimulated arachidonic acid release in rabbit renal vascular smooth muscle cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 170nMAssay Description:Inhibition of [125I]glucagon binding towards Glucagon receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 40nMAssay Description:Binding affinity against endothelin A receptor from rabbit renal vascular smooth musclesMore data for this Ligand-Target Pair
Affinity DataIC50: 960nMAssay Description:Binding affinity measured in CHO cells stably transfected with the human endothelin B receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 130nMAssay Description:Inhibitory concentration was evaluated by measuring the binding affinity at the Endothelin B receptor in rat cerebellar membranesMore data for this Ligand-Target Pair
Affinity DataIC50: 15nMAssay Description:Inhibition of ET-1 binding to Endothelin A receptor in cultured rabbit renal artery vascular smooth muscle cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 150nMAssay Description:Inhibition of ET-1 binding to Endothelin B receptor in cultured rat cerebellar membranesMore data for this Ligand-Target Pair
Affinity DataIC50: 180nMAssay Description:Inhibition of [125I]glucagon binding towards Glucagon receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 58nMAssay Description:Inhibition of binding to Endothelin A receptor of rabbit renal vascular smooth muscle cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 20nMAssay Description:Inhibition of ET-1 stimulated arachidonic acid release in CHO cells expressing rat ET- B receptorsMore data for this Ligand-Target Pair