BDBM50032241 CHEMBL2441067

SMILES Fc1ccc2N(CNS(=O)(=O)c2c1)C1CC1

InChI Key InChIKey=FLTMTBPCYAZIKM-UHFFFAOYSA-N

Data  1 Kd  3 EC50

PDB links: 7 PDB IDs match this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50032241   

TargetGlutamate receptor 2(Homo sapiens (Human))
University Of Liege

Curated by ChEMBL
LigandPNGBDBM50032241(CHEMBL2441067)
Affinity DataKd:  350nMAssay Description:Binding affinity to GluA2-LBD-L483Y-N754S complex (unknown origin) by isothermal titration calorimetryMore data for this Ligand-Target Pair
TargetGlutamate receptor 2(Rattus norvegicus)
University Of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50032241(CHEMBL2441067)
Affinity DataEC50:  900nMAssay Description:Positive allosteric modulation of GluA2 receptor in rat embryonic cortex neuron assessed as increase of AMPA-induced membrane depolarization by fluor...More data for this Ligand-Target Pair
TargetGlutamate receptor 2(Homo sapiens (Human))
University Of Liege

Curated by ChEMBL
LigandPNGBDBM50032241(CHEMBL2441067)
Affinity DataEC50:  813nMAssay Description:Positive allosteric modulation of GluA2 (Q) flop isoform (unknown origin) expressed in HEK293 cells assessed as potentiation of glutamate-evoked calc...More data for this Ligand-Target Pair
TargetGlutamate receptor 2(Homo sapiens (Human))
University Of Liege

Curated by ChEMBL
LigandPNGBDBM50032241(CHEMBL2441067)
Affinity DataEC50:  810nMAssay Description:Positive allosteric modulation of GluA2 (Q) flop isoform (unknown origin) expressed in HEK293 cells assessed as potentiation of glutamate-evoked calc...More data for this Ligand-Target Pair