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BDBM50032295 CHEMBL3353490

SMILES: CN(Cc1ccc(Cl)cc1)C(=O)C1(C)CCN1C(=O)Cc1cccc(c1)-c1ccsc1

InChI Key: InChIKey=BIJJHCROKDEVOL-UHFFFAOYNA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50032295   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Free fatty acid receptor 2


(Homo sapiens (Human))
BDBM50032295
PNG
(CHEMBL3353490)
Show SMILES CN(Cc1ccc(Cl)cc1)C(=O)C1(C)CCN1C(=O)Cc1cccc(c1)-c1ccsc1
Show InChI InChI=1/C25H25ClN2O2S/c1-25(24(30)27(2)16-18-6-8-22(26)9-7-18)11-12-28(25)23(29)15-19-4-3-5-20(14-19)21-10-13-31-17-21/h3-10,13-14,17H,11-12,15-16H2,1-2H3
Reactome pathway
KEGG

UniProtKB/SwissProt
UniProtKB/TrEMBL

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 5.80E+3n/an/an/an/an/an/a



Galapagos

Curated by ChEMBL


Assay Description
Antagonist activity against human FFA2 receptor expressed in HEK293 cells assessed as inhibition of sodium acetate-induced calcium mobilization


J Med Chem 57: 10044-57 (2014)


Article DOI: 10.1021/jm5012885
BindingDB Entry DOI: 10.7270/Q29S1SM9
More data for this
Ligand-Target Pair