BindingDB logo
myBDB logout

BDBM50032298 CHEMBL3353488

SMILES: CN(Cc1ccc(Cl)cc1)C(=O)C1(C)CCN1C(=O)Cc1ccc(cc1)-c1ccccc1

InChI Key: InChIKey=DXADTEIDFFSVKJ-UHFFFAOYNA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50032298   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Free fatty acid receptor 2


(Homo sapiens (Human))
BDBM50032298
PNG
(CHEMBL3353488)
Show SMILES CN(Cc1ccc(Cl)cc1)C(=O)C1(C)CCN1C(=O)Cc1ccc(cc1)-c1ccccc1
Show InChI InChI=1/C27H27ClN2O2/c1-27(26(32)29(2)19-21-10-14-24(28)15-11-21)16-17-30(27)25(31)18-20-8-12-23(13-9-20)22-6-4-3-5-7-22/h3-15H,16-19H2,1-2H3
Reactome pathway
KEGG

UniProtKB/SwissProt
UniProtKB/TrEMBL

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a>1.00E+4n/an/an/an/an/an/a



Galapagos

Curated by ChEMBL


Assay Description
Antagonist activity against human FFA2 receptor expressed in HEK293 cells assessed as inhibition of sodium acetate-induced calcium mobilization


J Med Chem 57: 10044-57 (2014)


Article DOI: 10.1021/jm5012885
BindingDB Entry DOI: 10.7270/Q29S1SM9
More data for this
Ligand-Target Pair