BindingDB logo
myBDB logout

BDBM50032448 CHEMBL3354153

SMILES: C[C@@H]1OC(=O)[C@@H]1NC(=O)OCc1cc2cc(C)ccc2s1

InChI Key: InChIKey=MOOHXSKBWZMWLQ-TVQRCGJNSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50032448   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
N-acylethanolamine-hydrolyzing acid amidase (NAAA)


(Rattus norvegicus (Rat))
BDBM50032448
PNG
(CHEMBL3354153)
Show SMILES C[C@@H]1OC(=O)[C@@H]1NC(=O)OCc1cc2cc(C)ccc2s1
Show InChI InChI=1S/C15H15NO4S/c1-8-3-4-12-10(5-8)6-11(21-12)7-19-15(18)16-13-9(2)20-14(13)17/h3-6,9,13H,7H2,1-2H3,(H,16,18)/t9-,13+/m0/s1
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 13n/an/an/an/an/an/a



Istituto Italiano di Tecnologia

Curated by ChEMBL


Assay Description
Inhibition of NAAA in Sprague-Dawley rat lung assessed as inhibition of hydrolysis of 10-cis-heptadecenoylethanolamide by UPLC/MS method


J Med Chem 57: 10101-11 (2014)


Article DOI: 10.1021/jm501455s
BindingDB Entry DOI: 10.7270/Q26111W8
More data for this
Ligand-Target Pair
N-acylethanolamine-hydrolyzing acid amidase (NAAA)


(Rattus norvegicus (Rat))
BDBM50032448
PNG
(CHEMBL3354153)
Show SMILES C[C@@H]1OC(=O)[C@@H]1NC(=O)OCc1cc2cc(C)ccc2s1
Show InChI InChI=1S/C15H15NO4S/c1-8-3-4-12-10(5-8)6-11(21-12)7-19-15(18)16-13-9(2)20-14(13)17/h3-6,9,13H,7H2,1-2H3,(H,16,18)/t9-,13+/m0/s1
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 13n/an/an/an/an/an/a



Istituto Italiano di Tecnologia

Curated by ChEMBL


Assay Description
Inhibition of NAAA in Sprague-Dawley rat lung assessed as inhibition of hydrolysis of 10-cis-heptadecenoylethanolamide by UPLC/MS method


J Med Chem 57: 10101-11 (2014)


Article DOI: 10.1021/jm501455s
BindingDB Entry DOI: 10.7270/Q26111W8
More data for this
Ligand-Target Pair