BDBM50032525 17-cyclopropylmethyl-4,10-dihydroxy-3-methoxy-17-azatetracyclo[7.5.3.01,10.02,7]heptadeca-2(7),3,5-trien-13-one::CHEMBL104310

SMILES COc1c(O)ccc2CC3N(CC4CC4)CCC4(CC(=O)CC[C@@]34O)c12

InChI Key

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50032525   

TargetKappa-type opioid receptor(Guinea pig)
University of Innsbruck

Curated by ChEMBL
LigandPNGBDBM50032525(17-cyclopropylmethyl-4,10-dihydroxy-3-methoxy-17-a...)
Affinity DataKi:  23nMAssay Description:Binding affinity was evaluated by measuring the ability to displace [3H]U-69593 radioligand binding from Opioid receptor kappa 1 in guinea pig brain ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2012
Entry Details Article
PubMed
TargetMu-type opioid receptor(Guinea pig)
University of Innsbruck

Curated by ChEMBL
LigandPNGBDBM50032525(17-cyclopropylmethyl-4,10-dihydroxy-3-methoxy-17-a...)
Affinity DataKi:  54nMAssay Description:In vivo binding affinity was evaluated by measuring the ability to displace [3H]DAMGO radioligand binding from Opioid receptor mu 1 in guinea pig bra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2012
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Human)
University of Innsbruck

Curated by ChEMBL
LigandPNGBDBM50032525(17-cyclopropylmethyl-4,10-dihydroxy-3-methoxy-17-a...)
Affinity DataKi:  334nMAssay Description:In vivo binding affinity was evaluated by measuring the ability to displace [3H]DPDPE radioligand binding from delta opioid receptor in guinea pig br...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2012
Entry Details Article
PubMed