BindingDB logo
myBDB logout

BDBM50032548 (3,4-Dimethyl-phenyl)-[2-methyl-1-(2-morpholin-4-yl-ethyl)-1H-indol-3-yl]-methanone::CHEMBL78995

SMILES: Cc1c(C(=O)c2ccc(C)c(C)c2)c2ccccc2n1CCN1CCOCC1

InChI Key: InChIKey=QPFANIPLVKQNJA-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50032548   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Cannabinoid receptor 1


(Rattus norvegicus (rat))
BDBM50032548
PNG
((3,4-Dimethyl-phenyl)-[2-methyl-1-(2-morpholin-4-y...)
Show SMILES Cc1c(C(=O)c2ccc(C)c(C)c2)c2ccccc2n1CCN1CCOCC1
Show InChI InChI=1S/C24H28N2O2/c1-17-8-9-20(16-18(17)2)24(27)23-19(3)26(22-7-5-4-6-21(22)23)11-10-25-12-14-28-15-13-25/h4-9,16H,10-15H2,1-3H3
PDB

Reactome pathway
KEGG

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 140n/an/an/an/an/an/a



Sanofi Research Division

Curated by ChEMBL


Assay Description
Concentration of compound required to inhibit 50% of [3H]-WIN- 55212 binding to Cannabinoid receptor 1 in rat cerebellum membranes.


J Med Chem 38: 3094-105 (1995)


Article DOI: 10.1021/jm00016a013
BindingDB Entry DOI: 10.7270/Q2DN442Z
More data for this
Ligand-Target Pair