BDBM50032675 4-[1-(3,5,5,8,8-pentamethyl-5,6,7,8-tetrahydronaphthalen-2-yl)vinyl]benzoic acid::BEXAROTENE::CHEMBL1023::p-(1-(5,6,7,8-Tetrahydro-3,5,5,8,8-pentamethyl-2-naphthyl)vinyl)benzoic acid

SMILES: Cc1cc2c(cc1C(=C)c3ccc(cc3)C(=O)O)C(CCC2(C)C)(C)C

InChI Key: InChIKey=NAVMQTYZDKMPEU-UHFFFAOYSA-N

Data: 34 KI  8 IC50  22 Kd  57 EC50

PDB links: 2 PDB IDs match this monomer.

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 127 hits for monomerid = 50032675   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Retinoic acid receptor RXR-alpha (Human)	BDBM50032675 (4-[1-(3,5,5,8,8-pentamethyl-5,6,7,8-tetrahydronaph...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	36	n/a	n/a	n/a	7.4	4
TBA									Citation and Details
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Retinoic acid receptor RXR-alpha (Human)	BDBM50032675 (4-[1-(3,5,5,8,8-pentamethyl-5,6,7,8-tetrahydronaph...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	7	n/a	n/a	n/a	7.4	4
TBA									Citation and Details
					More data for this Ligand-Target Pair
Retinoic acid receptor RXR-alpha (Human)	BDBM50032675 (4-[1-(3,5,5,8,8-pentamethyl-5,6,7,8-tetrahydronaph...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	26	n/a	n/a	n/a	7.4	4
TBA									Citation and Details
					More data for this Ligand-Target Pair
Retinoic acid receptor RXR-alpha (Human)	BDBM50032675 (4-[1-(3,5,5,8,8-pentamethyl-5,6,7,8-tetrahydronaph...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	42	n/a	n/a	n/a	7.4	4
TBA									Citation and Details
					More data for this Ligand-Target Pair
Retinoic acid receptor RXR-alpha (Human)	BDBM50032675 (4-[1-(3,5,5,8,8-pentamethyl-5,6,7,8-tetrahydronaph...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	51	n/a	n/a	n/a	7.4	4
TBA									Citation and Details
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Dimer of Retinoic acid receptor RXR-alpha (Human)	BDBM50032675 (4-[1-(3,5,5,8,8-pentamethyl-5,6,7,8-tetrahydronaph...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	28	n/a	n/a	n/a	7.4	4
TBA									Citation and Details
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Dimer of Retinoic acid receptor RXR-alpha (Human)	BDBM50032675 (4-[1-(3,5,5,8,8-pentamethyl-5,6,7,8-tetrahydronaph...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	18	n/a	n/a	n/a	7.4	4
TBA									Citation and Details
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ATP-binding cassette sub-family C member 2 (Human)	BDBM50032675 (4-[1-(3,5,5,8,8-pentamethyl-5,6,7,8-tetrahydronaph...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.33E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
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ATP-binding cassette sub-family C member 4 (Human)	BDBM50032675 (4-[1-(3,5,5,8,8-pentamethyl-5,6,7,8-tetrahydronaph...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.33E+5	n/a	n/a	n/a	n/a	n/a	n/a
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ATP-binding cassette sub-family C member 3 (Human)	BDBM50032675 (4-[1-(3,5,5,8,8-pentamethyl-5,6,7,8-tetrahydronaph...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.33E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
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Bile salt export pump (Human)	BDBM50032675 (4-[1-(3,5,5,8,8-pentamethyl-5,6,7,8-tetrahydronaph...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.33E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Retinoic acid receptor RXR-gamma (Human)	BDBM50032675 (4-[1-(3,5,5,8,8-pentamethyl-5,6,7,8-tetrahydronaph...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	25	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Retinoic acid receptor beta (Human)	BDBM50032675 (4-[1-(3,5,5,8,8-pentamethyl-5,6,7,8-tetrahydronaph...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Retinoic acid receptor RXR-beta (Human)	BDBM50032675 (4-[1-(3,5,5,8,8-pentamethyl-5,6,7,8-tetrahydronaph...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	24	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Retinoic acid receptor RXR-alpha (Human)	BDBM50032675 (4-[1-(3,5,5,8,8-pentamethyl-5,6,7,8-tetrahydronaph...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	33	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Retinoic acid receptor gamma (Human)	BDBM50032675 (4-[1-(3,5,5,8,8-pentamethyl-5,6,7,8-tetrahydronaph...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Retinoic acid receptor alpha (Human)	BDBM50032675 (4-[1-(3,5,5,8,8-pentamethyl-5,6,7,8-tetrahydronaph...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a
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Oxysterols receptor LXR-beta (Human)	BDBM50032675 (4-[1-(3,5,5,8,8-pentamethyl-5,6,7,8-tetrahydronaph...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	434	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Oxysterols receptor LXR-alpha (Human)	BDBM50032675 (4-[1-(3,5,5,8,8-pentamethyl-5,6,7,8-tetrahydronaph...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	196	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Retinoic acid receptor RXR-alpha (Human)	BDBM50032675 (4-[1-(3,5,5,8,8-pentamethyl-5,6,7,8-tetrahydronaph...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	36	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Retinoic acid receptor RXR-gamma (Mouse)	BDBM50032675 (4-[1-(3,5,5,8,8-pentamethyl-5,6,7,8-tetrahydronaph...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	29	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Retinoic acid receptor RXR-beta (Mouse)	BDBM50032675 (4-[1-(3,5,5,8,8-pentamethyl-5,6,7,8-tetrahydronaph...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	25	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Retinoic acid receptor RXR-alpha (Human)	BDBM50032675 (4-[1-(3,5,5,8,8-pentamethyl-5,6,7,8-tetrahydronaph...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	28	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Retinoic acid receptor RXR-gamma (Mouse)	BDBM50032675 (4-[1-(3,5,5,8,8-pentamethyl-5,6,7,8-tetrahydronaph...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	20	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Retinoic acid receptor RXR-beta (Mouse)	BDBM50032675 (4-[1-(3,5,5,8,8-pentamethyl-5,6,7,8-tetrahydronaph...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	21	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Retinoic acid receptor RXR-alpha (Human)	BDBM50032675 (4-[1-(3,5,5,8,8-pentamethyl-5,6,7,8-tetrahydronaph...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	42	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Retinoic acid receptor RXR-beta (Human)	BDBM50032675 (4-[1-(3,5,5,8,8-pentamethyl-5,6,7,8-tetrahydronaph...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	112	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Retinoic acid receptor RXR-gamma (Human)	BDBM50032675 (4-[1-(3,5,5,8,8-pentamethyl-5,6,7,8-tetrahydronaph...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	122	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Retinoic acid receptor RXR-alpha (Human)	BDBM50032675 (4-[1-(3,5,5,8,8-pentamethyl-5,6,7,8-tetrahydronaph...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	149	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Retinoic acid receptor alpha (Human)	BDBM50032675 (4-[1-(3,5,5,8,8-pentamethyl-5,6,7,8-tetrahydronaph...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Retinoic acid receptor RXR-gamma (Mouse)	BDBM50032675 (4-[1-(3,5,5,8,8-pentamethyl-5,6,7,8-tetrahydronaph...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	29	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Retinoic acid receptor RXR-alpha (Human)	BDBM50032675 (4-[1-(3,5,5,8,8-pentamethyl-5,6,7,8-tetrahydronaph...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	33	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Retinoic acid receptor gamma (Human)	BDBM50032675 (4-[1-(3,5,5,8,8-pentamethyl-5,6,7,8-tetrahydronaph...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Retinoic acid receptor beta (Human)	BDBM50032675 (4-[1-(3,5,5,8,8-pentamethyl-5,6,7,8-tetrahydronaph...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Retinoic acid receptor RXR-beta (Mouse)	BDBM50032675 (4-[1-(3,5,5,8,8-pentamethyl-5,6,7,8-tetrahydronaph...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	24	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Retinoic acid receptor RXR-gamma (Mouse)	BDBM50032675 (4-[1-(3,5,5,8,8-pentamethyl-5,6,7,8-tetrahydronaph...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	25	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Retinoic acid receptor beta (Human)	BDBM50032675 (4-[1-(3,5,5,8,8-pentamethyl-5,6,7,8-tetrahydronaph...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Retinoic acid receptor RXR-beta (Mouse)	BDBM50032675 (4-[1-(3,5,5,8,8-pentamethyl-5,6,7,8-tetrahydronaph...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	21	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Retinoic acid receptor alpha (Human)	BDBM50032675 (4-[1-(3,5,5,8,8-pentamethyl-5,6,7,8-tetrahydronaph...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Retinoic acid receptor RXR-alpha (Human)	BDBM50032675 (4-[1-(3,5,5,8,8-pentamethyl-5,6,7,8-tetrahydronaph...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	14	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Retinoic acid receptor gamma (Human)	BDBM50032675 (4-[1-(3,5,5,8,8-pentamethyl-5,6,7,8-tetrahydronaph...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Retinoic acid receptor alpha (Human)	BDBM50032675 (4-[1-(3,5,5,8,8-pentamethyl-5,6,7,8-tetrahydronaph...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	6	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Retinoic acid receptor gamma (Human)	BDBM50032675 (4-[1-(3,5,5,8,8-pentamethyl-5,6,7,8-tetrahydronaph...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	648	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Retinoic acid receptor RXR-alpha (Human)	BDBM50032675 (4-[1-(3,5,5,8,8-pentamethyl-5,6,7,8-tetrahydronaph...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	28	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Retinoic acid receptor beta (Human)	BDBM50032675 (4-[1-(3,5,5,8,8-pentamethyl-5,6,7,8-tetrahydronaph...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	282	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Retinoic acid receptor RXR-gamma (Human)	BDBM50032675 (4-[1-(3,5,5,8,8-pentamethyl-5,6,7,8-tetrahydronaph...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	20	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Retinoic acid receptor RXR-beta (Human)	BDBM50032675 (4-[1-(3,5,5,8,8-pentamethyl-5,6,7,8-tetrahydronaph...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	25	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Retinoic acid receptor RXR-alpha (Human)	BDBM50032675 (4-[1-(3,5,5,8,8-pentamethyl-5,6,7,8-tetrahydronaph...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	210	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Retinoic acid receptor RXR-gamma (Human)	BDBM50032675 (4-[1-(3,5,5,8,8-pentamethyl-5,6,7,8-tetrahydronaph...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	25	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Retinoic acid receptor RXR-alpha (Human)	BDBM50032675 (4-[1-(3,5,5,8,8-pentamethyl-5,6,7,8-tetrahydronaph...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	210	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair