BindingDB logo
myBDB logout

BDBM50032898 CHEMBL3342788

InChI string: InChI=1S/C32H26F7N3O5S/c1-16(2)30-41-28(29(46-30)18-5-8-21(9-6-18)47-32(37,38)39)22-11-19(20-12-24(33)23(15-43)26(13-20)48(4,44)45)7-10-25(22)42-14-27(31(34,35)36)40-17(42)3/h5-14,16,43H,15H2,1-4H3

SMILES: CC(C)c1nc(c(o1)-c1ccc(OC(F)(F)F)cc1)-c1cc(ccc1-n1cc(nc1C)C(F)(F)F)-c1cc(F)c(CO)c(c1)S(C)(=O)=O

InChI Key: InChIKey=NRSDWNVESRFSKT-UHFFFAOYSA-N

Data: 1 EC50

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50032898   
Target
(Institution)
LigandTarget
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Liver X receptor beta (LXRB)


(Homo sapiens (Human))
BDBM50032898
PNG
(CHEMBL3342788)
Show SMILES CC(C)c1nc(c(o1)-c1ccc(OC(F)(F)F)cc1)-c1cc(ccc1-n1cc(nc1C)C(F)(F)F)-c1cc(F)c(CO)c(c1)S(C)(=O)=O
Show InChI InChI=1S/C32H26F7N3O5S/c1-16(2)30-41-28(29(46-30)18-5-8-21(9-6-18)47-32(37,38)39)22-11-19(20-12-24(33)23(15-43)26(13-20)48(4,44)45)7-10-25(22)42-14-27(31(34,35)36)40-17(42)3/h5-14,16,43H,15H2,1-4H3
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

AffyNet 
Article
PubMed
n/an/an/an/a 16n/an/an/an/a



Therachem Research Medilab (India) Pvt. Ltd.

Curated by ChEMBL


Assay Description
Agonist activity at human LXRbeta expressed in CV1 cells after 20 hrs by luciferase reporter co-transfection assay


ACS Med Chem Lett 5: 1186-7 (2014)

More data for this
Ligand-Target Pair