BDBM50033110 ALFUZOSIN::CHEMBL709::N-{3-[(4-amino-6,7-dimethoxyquinazolin-2-yl)(methyl)amino]propyl}tetrahydrofuran-2-carboxamide

SMILES: COc1cc2nc(nc(N)c2cc1OC)N(C)CCCNC(=O)C1CCCO1

InChI Key: InChIKey=WNMJYKCGWZFFKR-UHFFFAOYSA-N

Data: 8 KI  12 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 20 hits for monomerid = 50033110   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Alpha-1A/Alpha-1B/Alpha-1D adrenergic receptor (Human)	BDBM50033110 (N-{3-[(4-amino-6,7-dimethoxyquinazolin-2-yl)(methy...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	23	n/a	n/a	n/a	n/a	n/a	n/a
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Solute carrier family 22 member 1 (Human)	BDBM50033110 (N-{3-[(4-amino-6,7-dimethoxyquinazolin-2-yl)(methy...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.49E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Potassium voltage-gated channel subfamily H member 2 (Human)	BDBM50033110 (N-{3-[(4-amino-6,7-dimethoxyquinazolin-2-yl)(methy...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Potassium voltage-gated channel subfamily H member 2 (Human)	BDBM50033110 (N-{3-[(4-amino-6,7-dimethoxyquinazolin-2-yl)(methy...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.26E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Potassium voltage-gated channel subfamily E/KQT member 1 (Human)	BDBM50033110 (N-{3-[(4-amino-6,7-dimethoxyquinazolin-2-yl)(methy...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.26E+5	n/a	n/a	n/a	n/a	n/a	n/a
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Potassium voltage-gated channel subfamily H member 2 (Human)	BDBM50033110 (N-{3-[(4-amino-6,7-dimethoxyquinazolin-2-yl)(methy...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.26E+5	n/a	n/a	n/a	n/a	n/a	n/a
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Sodium channel protein type 5 subunit alpha (Human)	BDBM50033110 (N-{3-[(4-amino-6,7-dimethoxyquinazolin-2-yl)(methy...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.58E+6	n/a	n/a	n/a	n/a	n/a	n/a
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Potassium voltage-gated channel subfamily D member 3 (Human)	BDBM50033110 (N-{3-[(4-amino-6,7-dimethoxyquinazolin-2-yl)(methy...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.00E+6	n/a	n/a	n/a	n/a	n/a	n/a
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Voltage-dependent L-type calcium channel subunit alpha-1C (Human)	BDBM50033110 (N-{3-[(4-amino-6,7-dimethoxyquinazolin-2-yl)(methy...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
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Sodium channel protein type 5 subunit alpha (Human)	BDBM50033110 (N-{3-[(4-amino-6,7-dimethoxyquinazolin-2-yl)(methy...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
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Acetylcholinesterase (Human)	BDBM50033110 (N-{3-[(4-amino-6,7-dimethoxyquinazolin-2-yl)(methy...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	18	n/a	n/a	n/a	n/a	n/a	n/a
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Bile salt export pump (Human)	BDBM50033110 (N-{3-[(4-amino-6,7-dimethoxyquinazolin-2-yl)(methy...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.33E+5	n/a	n/a	n/a	n/a	n/a	n/a
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Alpha-1B adrenergic receptor (Human)	BDBM50033110 (N-{3-[(4-amino-6,7-dimethoxyquinazolin-2-yl)(methy...) Show SMILES Show InChI	GoogleScholar	UniChem		2.80	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Alpha-1A adrenergic receptor (Human)	BDBM50033110 (N-{3-[(4-amino-6,7-dimethoxyquinazolin-2-yl)(methy...) Show SMILES Show InChI	GoogleScholar	UniChem		3.16	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Alpha-1D adrenergic receptor (Rat)	BDBM50033110 (N-{3-[(4-amino-6,7-dimethoxyquinazolin-2-yl)(methy...) Show SMILES Show InChI	GoogleScholar	UniChem		3.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Alpha-1D adrenergic receptor (Human)	BDBM50033110 (N-{3-[(4-amino-6,7-dimethoxyquinazolin-2-yl)(methy...) Show SMILES Show InChI	GoogleScholar	UniChem		3.60	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Alpha-1A adrenergic receptor (Human)	BDBM50033110 (N-{3-[(4-amino-6,7-dimethoxyquinazolin-2-yl)(methy...) Show SMILES Show InChI	GoogleScholar	UniChem		8.20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Alpha-1B adrenergic receptor (Mouse)	BDBM50033110 (N-{3-[(4-amino-6,7-dimethoxyquinazolin-2-yl)(methy...) Show SMILES Show InChI	GoogleScholar	UniChem		10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Alpha-1B adrenergic receptor (Human)	BDBM50033110 (N-{3-[(4-amino-6,7-dimethoxyquinazolin-2-yl)(methy...) Show SMILES Show InChI	GoogleScholar	UniChem		12	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Alpha-1A adrenergic receptor (Bovine)	BDBM50033110 (N-{3-[(4-amino-6,7-dimethoxyquinazolin-2-yl)(methy...) Show SMILES Show InChI	GoogleScholar	UniChem		23	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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