BDBM50033111 1-(4-Amino-6,7-dimethoxy-2-quinazolinyl)-4-((tetrahydro-2-furanyl)carbonyl)piperazine::6,7-dimethoxy-2-[4-(tetrahydrofuran-2-ylcarbonyl)piperazin-1-yl]quinazolin-4-amine::CHEMBL611::TERAZOSIN::Terazosine

SMILES: COc1cc2nc(nc(N)c2cc1OC)N1CCN(CC1)C(=O)C1CCCO1

InChI Key: InChIKey=VCKUSRYTPJJLNI-UHFFFAOYSA-N

Data: 64 KI  7 IC50  4 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 75 hits for monomerid = 50033111   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Alpha-1A adrenergic receptor (Human)	BDBM50033111 (6,7-dimethoxy-2-[4-(tetrahydrofuran-2-ylcarbonyl)p...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	52	n/a	n/a	n/a	n/a
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Alpha-1A/Alpha-1B/Alpha-1D adrenergic receptor (Human)	BDBM50033111 (6,7-dimethoxy-2-[4-(tetrahydrofuran-2-ylcarbonyl)p...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	5	n/a	n/a	n/a	n/a	n/a	n/a
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Solute carrier family 22 member 1 (Human)	BDBM50033111 (6,7-dimethoxy-2-[4-(tetrahydrofuran-2-ylcarbonyl)p...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.37E+4	n/a	n/a	n/a	n/a	n/a	n/a
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ATP-binding cassette sub-family C member 4 (Human)	BDBM50033111 (6,7-dimethoxy-2-[4-(tetrahydrofuran-2-ylcarbonyl)p...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3.68E+4	n/a	n/a	n/a	n/a	n/a	n/a
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ATP-binding cassette sub-family C member 3 (Human)	BDBM50033111 (6,7-dimethoxy-2-[4-(tetrahydrofuran-2-ylcarbonyl)p...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.33E+5	n/a	n/a	n/a	n/a	n/a	n/a
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ATP-binding cassette sub-family C member 2 (Human)	BDBM50033111 (6,7-dimethoxy-2-[4-(tetrahydrofuran-2-ylcarbonyl)p...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.33E+5	n/a	n/a	n/a	n/a	n/a	n/a
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Bile salt export pump (Human)	BDBM50033111 (6,7-dimethoxy-2-[4-(tetrahydrofuran-2-ylcarbonyl)p...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.33E+5	n/a	n/a	n/a	n/a	n/a	n/a
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Potassium voltage-gated channel subfamily H member 2 (Human)	BDBM50033111 (6,7-dimethoxy-2-[4-(tetrahydrofuran-2-ylcarbonyl)p...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.78E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Alpha-1B adrenergic receptor (Human)	BDBM50033111 (6,7-dimethoxy-2-[4-(tetrahydrofuran-2-ylcarbonyl)p...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	1.70	n/a	n/a	n/a	n/a
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Alpha-1A adrenergic receptor (Human)	BDBM50033111 (6,7-dimethoxy-2-[4-(tetrahydrofuran-2-ylcarbonyl)p...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	51	n/a	n/a	n/a	n/a
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Alpha-1B adrenergic receptor (Human)	BDBM50033111 (6,7-dimethoxy-2-[4-(tetrahydrofuran-2-ylcarbonyl)p...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	0.5	n/a	n/a	n/a	n/a
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Alpha-1D adrenergic receptor (Human)	BDBM50033111 (6,7-dimethoxy-2-[4-(tetrahydrofuran-2-ylcarbonyl)p...) Show SMILES Show InChI	GoogleScholar	UniChem		0.660	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Alpha-1B adrenergic receptor (Golden hamster)	BDBM50033111 (6,7-dimethoxy-2-[4-(tetrahydrofuran-2-ylcarbonyl)p...) Show SMILES Show InChI	GoogleScholar	UniChem		0.690	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Alpha-1A adrenergic receptor (Rat)	BDBM50033111 (6,7-dimethoxy-2-[4-(tetrahydrofuran-2-ylcarbonyl)p...) Show SMILES Show InChI	GoogleScholar	UniChem		0.820	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Alpha-1D adrenergic receptor (Human)	BDBM50033111 (6,7-dimethoxy-2-[4-(tetrahydrofuran-2-ylcarbonyl)p...) Show SMILES Show InChI	GoogleScholar	UniChem		0.850	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Alpha-1D adrenergic receptor (Rat)	BDBM50033111 (6,7-dimethoxy-2-[4-(tetrahydrofuran-2-ylcarbonyl)p...) Show SMILES Show InChI	GoogleScholar	UniChem		1.01	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Alpha-1B adrenergic receptor (Human)	BDBM50033111 (6,7-dimethoxy-2-[4-(tetrahydrofuran-2-ylcarbonyl)p...) Show SMILES Show InChI	GoogleScholar	UniChem		1.15	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Alpha-1B adrenergic receptor (Human)	BDBM50033111 (6,7-dimethoxy-2-[4-(tetrahydrofuran-2-ylcarbonyl)p...) Show SMILES Show InChI	GoogleScholar	UniChem		1.20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Alpha-1B adrenergic receptor (Human)	BDBM50033111 (6,7-dimethoxy-2-[4-(tetrahydrofuran-2-ylcarbonyl)p...) Show SMILES Show InChI	GoogleScholar	UniChem		1.20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Alpha-1A adrenergic receptor (Human)	BDBM50033111 (6,7-dimethoxy-2-[4-(tetrahydrofuran-2-ylcarbonyl)p...) Show SMILES Show InChI	GoogleScholar	UniChem		1.82	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Alpha-1B adrenergic receptor (Human)	BDBM50033111 (6,7-dimethoxy-2-[4-(tetrahydrofuran-2-ylcarbonyl)p...) Show SMILES Show InChI	GoogleScholar	UniChem		1.90	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Alpha-1B adrenergic receptor (Rat)	BDBM50033111 (6,7-dimethoxy-2-[4-(tetrahydrofuran-2-ylcarbonyl)p...) Show SMILES Show InChI	GoogleScholar	UniChem		1.90	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Alpha-1B adrenergic receptor (Human)	BDBM50033111 (6,7-dimethoxy-2-[4-(tetrahydrofuran-2-ylcarbonyl)p...) Show SMILES Show InChI	GoogleScholar	UniChem		1.90	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Alpha-1B adrenergic receptor (Human)	BDBM50033111 (6,7-dimethoxy-2-[4-(tetrahydrofuran-2-ylcarbonyl)p...) Show SMILES Show InChI	GoogleScholar	UniChem		1.90	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Alpha-1D adrenergic receptor (Human)	BDBM50033111 (6,7-dimethoxy-2-[4-(tetrahydrofuran-2-ylcarbonyl)p...) Show SMILES Show InChI	GoogleScholar	UniChem		2	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Alpha-1A adrenergic receptor (Human)	BDBM50033111 (6,7-dimethoxy-2-[4-(tetrahydrofuran-2-ylcarbonyl)p...) Show SMILES Show InChI	GoogleScholar	UniChem		2	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Alpha-1D adrenergic receptor (Human)	BDBM50033111 (6,7-dimethoxy-2-[4-(tetrahydrofuran-2-ylcarbonyl)p...) Show SMILES Show InChI	GoogleScholar	UniChem		2	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Alpha-1A adrenergic receptor (Human)	BDBM50033111 (6,7-dimethoxy-2-[4-(tetrahydrofuran-2-ylcarbonyl)p...) Show SMILES Show InChI	GoogleScholar	UniChem		2	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Alpha-1B adrenergic receptor (Mouse)	BDBM50033111 (6,7-dimethoxy-2-[4-(tetrahydrofuran-2-ylcarbonyl)p...) Show SMILES Show InChI	GoogleScholar	UniChem		2	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Alpha-1A adrenergic receptor (Human)	BDBM50033111 (6,7-dimethoxy-2-[4-(tetrahydrofuran-2-ylcarbonyl)p...) Show SMILES Show InChI	GoogleScholar	UniChem		2.40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Alpha-1A adrenergic receptor (Bovine)	BDBM50033111 (6,7-dimethoxy-2-[4-(tetrahydrofuran-2-ylcarbonyl)p...) Show SMILES Show InChI	GoogleScholar	UniChem		2.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Alpha-1A adrenergic receptor (Human)	BDBM50033111 (6,7-dimethoxy-2-[4-(tetrahydrofuran-2-ylcarbonyl)p...) Show SMILES Show InChI	GoogleScholar	UniChem		2.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Alpha-1B adrenergic receptor (Human)	BDBM50033111 (6,7-dimethoxy-2-[4-(tetrahydrofuran-2-ylcarbonyl)p...) Show SMILES Show InChI	GoogleScholar	UniChem		2.60	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Alpha-1B adrenergic receptor (Human)	BDBM50033111 (6,7-dimethoxy-2-[4-(tetrahydrofuran-2-ylcarbonyl)p...) Show SMILES Show InChI	GoogleScholar	UniChem		2.68	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Alpha-1A adrenergic receptor (Human)	BDBM50033111 (6,7-dimethoxy-2-[4-(tetrahydrofuran-2-ylcarbonyl)p...) Show SMILES Show InChI	GoogleScholar	UniChem		2.90	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Alpha-1B adrenergic receptor (Hamster)	BDBM50033111 (6,7-dimethoxy-2-[4-(tetrahydrofuran-2-ylcarbonyl)p...) Show SMILES Show InChI	GoogleScholar	UniChem		3.16	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Alpha-1D adrenergic receptor (Rat)	BDBM50033111 (6,7-dimethoxy-2-[4-(tetrahydrofuran-2-ylcarbonyl)p...) Show SMILES Show InChI	GoogleScholar	UniChem		3.40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Alpha-1D adrenergic receptor (Human)	BDBM50033111 (6,7-dimethoxy-2-[4-(tetrahydrofuran-2-ylcarbonyl)p...) Show SMILES Show InChI	GoogleScholar	UniChem		3.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Alpha-1D adrenergic receptor (Human)	BDBM50033111 (6,7-dimethoxy-2-[4-(tetrahydrofuran-2-ylcarbonyl)p...) Show SMILES Show InChI	GoogleScholar	UniChem		3.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Alpha-1D adrenergic receptor (Human)	BDBM50033111 (6,7-dimethoxy-2-[4-(tetrahydrofuran-2-ylcarbonyl)p...) Show SMILES Show InChI	GoogleScholar	UniChem		3.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Alpha-1D adrenergic receptor (Human)	BDBM50033111 (6,7-dimethoxy-2-[4-(tetrahydrofuran-2-ylcarbonyl)p...) Show SMILES Show InChI	GoogleScholar	UniChem		3.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Alpha-1D adrenergic receptor (Human)	BDBM50033111 (6,7-dimethoxy-2-[4-(tetrahydrofuran-2-ylcarbonyl)p...) Show SMILES Show InChI	GoogleScholar	UniChem		3.70	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Alpha-1A adrenergic receptor (Rat)	BDBM50033111 (6,7-dimethoxy-2-[4-(tetrahydrofuran-2-ylcarbonyl)p...) Show SMILES Show InChI	GoogleScholar	UniChem		3.90	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Alpha-1A adrenergic receptor (Human)	BDBM50033111 (6,7-dimethoxy-2-[4-(tetrahydrofuran-2-ylcarbonyl)p...) Show SMILES Show InChI	GoogleScholar	UniChem		3.98	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Alpha-1A adrenergic receptor (Human)	BDBM50033111 (6,7-dimethoxy-2-[4-(tetrahydrofuran-2-ylcarbonyl)p...) Show SMILES Show InChI	GoogleScholar	UniChem		3.98	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Alpha-1A adrenergic receptor (Human)	BDBM50033111 (6,7-dimethoxy-2-[4-(tetrahydrofuran-2-ylcarbonyl)p...) Show SMILES Show InChI	GoogleScholar	UniChem		4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Alpha-1A adrenergic receptor (Human)	BDBM50033111 (6,7-dimethoxy-2-[4-(tetrahydrofuran-2-ylcarbonyl)p...) Show SMILES Show InChI	GoogleScholar	UniChem		4.20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Alpha-1A adrenergic receptor (Human)	BDBM50033111 (6,7-dimethoxy-2-[4-(tetrahydrofuran-2-ylcarbonyl)p...) Show SMILES Show InChI	GoogleScholar	UniChem		4.20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Alpha-1A adrenergic receptor (Rat)	BDBM50033111 (6,7-dimethoxy-2-[4-(tetrahydrofuran-2-ylcarbonyl)p...) Show SMILES Show InChI	GoogleScholar	UniChem		5.01	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Alpha-1A adrenergic receptor (Human)	BDBM50033111 (6,7-dimethoxy-2-[4-(tetrahydrofuran-2-ylcarbonyl)p...) Show SMILES Show InChI	GoogleScholar	UniChem		6.30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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