BDBM50033537 CHEMBL121060::N-[(3S,4R)-1-((S)-2-Hydroxy-2-phenyl-ethyl)-3-methyl-piperidin-4-yl]-N-phenyl-propionamide

SMILES CCC(=O)N([C@@H]1CCN(C[C@@H](O)c2ccccc2)C[C@@H]1C)c1ccccc1

InChI Key InChIKey=FRPRNNRJTCONEC-UHFFFAOYSA-N

Data  5 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50033537   

TargetKappa-type opioid receptor(Guinea pig)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50033537(N-[(3S,4R)-1-((S)-2-Hydroxy-2-phenyl-ethyl)-3-meth...)
Affinity DataKi: >0.5nMAssay Description:Binding affinity towards Opioid receptor kappa 1 using [3H]U-69593 as radioligand.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/31/2012
Entry Details Article
PubMed
TargetMu-type opioid receptor(Mouse)
Institute of Materia Medica

Curated by ChEMBL
LigandPNGBDBM50033537(N-[(3S,4R)-1-((S)-2-Hydroxy-2-phenyl-ethyl)-3-meth...)
Affinity DataKi:  2.89nMAssay Description:Inhibition against Opioid receptor mu 1 using [3H]- DAMGO radioligand.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Rat)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50033537(N-[(3S,4R)-1-((S)-2-Hydroxy-2-phenyl-ethyl)-3-meth...)
Affinity DataKi: >3nMAssay Description:Binding affinity towards Opioid receptor delta 1 using [3H]DADLE as radioligand.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/31/2012
Entry Details Article
PubMed
TargetMu-type opioid receptor(Rat)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50033537(N-[(3S,4R)-1-((S)-2-Hydroxy-2-phenyl-ethyl)-3-meth...)
Affinity DataKi:  16nMAssay Description:Binding affinity towards Opioid receptor mu 1 using [3H]DAMGO as radioligand.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/31/2012
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Mouse)
Institute of Materia Medica

Curated by ChEMBL
LigandPNGBDBM50033537(N-[(3S,4R)-1-((S)-2-Hydroxy-2-phenyl-ethyl)-3-meth...)
Affinity DataKi: >1.00E+3nMAssay Description:Inhibition against delta-opioid receptor using [3H]DPDPE radioligand.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed