BDBM50034273 4-Phenyl-4-(3-trifluoromethyl-benzyloxymethyl)-piperidine::CHEMBL281828

SMILES FC(F)(F)c1cccc(COCC2(CCNCC2)c2ccccc2)c1

InChI Key InChIKey=DZUQXMNESQQMDK-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50034273   

TargetSubstance-P receptor(Homo sapiens (Human))
Merck Sharp And Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50034273(4-Phenyl-4-(3-trifluoromethyl-benzyloxymethyl)-pip...)
Affinity DataIC50:  57nMAssay Description:Antagonistic activity against human Tachykinin receptor 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSubstance-P receptor(Homo sapiens (Human))
Merck Sharp And Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50034273(4-Phenyl-4-(3-trifluoromethyl-benzyloxymethyl)-pip...)
Affinity DataIC50:  57.5nMAssay Description:Binding affinity was measured against the Tachykinin receptor 1 in CHO-expressed hNK1 using [125I]SP.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSubstance-P receptor(Homo sapiens (Human))
Merck Sharp And Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50034273(4-Phenyl-4-(3-trifluoromethyl-benzyloxymethyl)-pip...)
Affinity DataIC50:  57nMAssay Description:Binding affinity at human tachykinin receptor 1 by measuring its ability to displace [125I]-labeled substance P from the cloned receptor expressed in...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed