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BDBM50034280 2-Chloro-5-((2E,6E)-3,7,11-trimethyl-dodeca-2,6,10-trienylamino)-benzoic acid::CHEMBL23751

SMILES: [#6]\[#6](-[#6])=[#6]/[#6]-[#6]\[#6](-[#6])=[#6]\[#6]-[#6]\[#6](-[#6])=[#6]\[#6]-[#7]-c1ccc(Cl)c(c1)-[#6](-[#8])=O

InChI Key: InChIKey=HHXKLPLAKJMLAI-IJUJUXHTSA-N

Data: 1 KI

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50034280   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Isoprenylcysteine carboxyl methyltransferase


(Rattus norvegicus)
BDBM50034280
PNG
(2-Chloro-5-((2E,6E)-3,7,11-trimethyl-dodeca-2,6,10...)
Show SMILES CC(C)=CCC\C(C)=C\CC\C(C)=C\CNc1ccc(Cl)c(c1)C(O)=O
Show InChI InChI=1S/C22H30ClNO2/c1-16(2)7-5-8-17(3)9-6-10-18(4)13-14-24-19-11-12-21(23)20(15-19)22(25)26/h7,9,11-13,15,24H,5-6,8,10,14H2,1-4H3,(H,25,26)/b17-9+,18-13+
KEGG

UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Patents

Article
PubMed
8.00E+3n/an/an/an/an/an/an/an/a



Institute for Biological Research

Curated by ChEMBL


Assay Description
Ability to inhibit prenylated protein methyltransferase (PPMTase) in cell free systems


J Med Chem 38: 1267-72 (1995)


Article DOI: 10.1021/jm00008a004
BindingDB Entry DOI: 10.7270/Q2N015KK
More data for this
Ligand-Target Pair