BDBM50034434 5-(5-Dimethylamino-naphthalene-1-sulfonylamino)-3-methyl-isoxazole-4-carboxylic acid ethyl ester::CHEMBL26206

SMILES CCOC(=O)c1c(C)noc1NS(=O)(=O)c1cccc2c(cccc12)N(C)C

InChI Key InChIKey=IENNCXYZSDIKGA-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50034434   

TargetEndothelin-1 receptor(Rat)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50034434(5-(5-Dimethylamino-naphthalene-1-sulfonylamino)-3-...)
Affinity DataIC50: 3.10E+4nMAssay Description:Antagonism of [125 I]ET-1 binding to the rat endothelin receptor in vascular smooth muscle VSM-A10 cells.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed