BDBM50034485 CHEMBL30077::N-[6-(3,4-Dimethyl-isoxazol-5-ylsulfamoyl)-naphthalen-1-yl]-acetamide

SMILES CC(=O)Nc1cccc2cc(ccc12)S(=O)(=O)Nc1onc(C)c1C

InChI Key InChIKey=DOYCEWNTYKDBOG-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50034485   

TargetEndothelin-1 receptor(RAT)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50034485(CHEMBL30077 | N-[6-(3,4-Dimethyl-isoxazol-5-ylsulf...)
Affinity DataIC50:  2.70E+3nMAssay Description:Inhibition of [125I]-endothelin-l binding to endothelin A receptor of rat thoracic aorta smooth muscle cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(RAT)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50034485(CHEMBL30077 | N-[6-(3,4-Dimethyl-isoxazol-5-ylsulf...)
Affinity DataIC50:  2.70E+3nMAssay Description:Antagonism of [125 I]ET-1 binding to the rat endothelin receptor in vascular smooth muscle VSM-A10 cells.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed