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BDBM50034735 CHEMBL446610::N-[1-(1-Oxy-pyridin-4-yl)-2-phenyl-ethyl]-2,2-diphenyl-acetamide

SMILES: [O-][n+]1ccc(cc1)C(Cc1ccccc1)NC(=O)C(c1ccccc1)c1ccccc1

InChI Key: InChIKey=TURQUOABEVFVRO-UHFFFAOYNA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50034735   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Sterol O-acyltransferase, Soat


(Rattus norvegicus)
BDBM50034735
PNG
(CHEMBL446610 | N-[1-(1-Oxy-pyridin-4-yl)-2-phenyl-...)
Show SMILES [O-][n+]1ccc(cc1)C(Cc1ccccc1)NC(=O)C(c1ccccc1)c1ccccc1
Show InChI InChI=1/C27H24N2O2/c30-27(26(23-12-6-2-7-13-23)24-14-8-3-9-15-24)28-25(20-21-10-4-1-5-11-21)22-16-18-29(31)19-17-22/h1-19,25-26H,20H2,(H,28,30)
PDB

KEGG

UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a>1.00E+4n/an/an/an/an/an/a



Schering-Plough Research Institute

Curated by ChEMBL


Assay Description
In vitro inhibition of acyl coenzyme A:cholesterol acyltransferase 1, rat liver microsomal assay


J Med Chem 38: 1600-7 (1995)


Article DOI: 10.1021/jm00010a004
BindingDB Entry DOI: 10.7270/Q26T0KN9
More data for this
Ligand-Target Pair