BDBM50034842 (2R,4S)-5-Biphenyl-4-yl-4-(3-carboxy-propionylamino)-2-methyl-pentanoic acid::CHEMBL417007::US10123984, Compound 21a(R,S)::US11547687, Comparative Compound B::US20230285340, Comparative Compound B

SMILES: C[C@H](C[C@@H](Cc1ccc(cc1)-c1ccccc1)NC(=O)CCC(O)=O)C(O)=O

InChI Key: InChIKey=DOBNVUFHFMVMDB-UHFFFAOYSA-N

Data: 2 KI  6 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50034842   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Neprilysin (Human)	BDBM50034842 ((2R,4S)-5-Biphenyl-4-yl-4-(3-carboxy-propionylamin...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	5	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Neprilysin/Angiotensin-converting enzyme (Human)	BDBM50034842 ((2R,4S)-5-Biphenyl-4-yl-4-(3-carboxy-propionylamin...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	190	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Neprilysin (Rat)	BDBM50034842 ((2R,4S)-5-Biphenyl-4-yl-4-(3-carboxy-propionylamin...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	5	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Neprilysin (Human)	BDBM50034842 ((2R,4S)-5-Biphenyl-4-yl-4-(3-carboxy-propionylamin...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	6	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Neprilysin (Human)	BDBM50034842 ((2R,4S)-5-Biphenyl-4-yl-4-(3-carboxy-propionylamin...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	20	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Angiotensin-converting enzyme (Human)	BDBM50034842 ((2R,4S)-5-Biphenyl-4-yl-4-(3-carboxy-propionylamin...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Neprilysin/Angiotensin-converting enzyme (Human)	BDBM50034842 ((2R,4S)-5-Biphenyl-4-yl-4-(3-carboxy-propionylamin...) Show SMILES Show InChI	GoogleScholar	UniChem		6.31	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Neprilysin (Human)	BDBM50034842 ((2R,4S)-5-Biphenyl-4-yl-4-(3-carboxy-propionylamin...) Show SMILES Show InChI	GoogleScholar	UniChem		6.31	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair