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BDBM50034886 CHEMBL3338106

SMILES: Cc1c(Cc2ccccc2S(=O)(=O)c2ccc(Cl)cc2)c2c(CCNC2=O)n1CC(O)=O

InChI Key: InChIKey=UUQIPFMOPZJVIO-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50034886   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
G protein-coupled receptor 44


(Homo sapiens (Human))
BDBM50034886
PNG
(CHEMBL3338106)
Show SMILES Cc1c(Cc2ccccc2S(=O)(=O)c2ccc(Cl)cc2)c2c(CCNC2=O)n1CC(O)=O
Show InChI InChI=1S/C23H21ClN2O5S/c1-14-18(22-19(10-11-25-23(22)29)26(14)13-21(27)28)12-15-4-2-3-5-20(15)32(30,31)17-8-6-16(24)7-9-17/h2-9H,10-13H2,1H3,(H,25,29)(H,27,28)
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Similars

Article
PubMed
n/an/a 8.5n/an/an/an/an/an/a



Rhône-Poulenc Rorer

Curated by ChEMBL


Assay Description
Antagonist activity at CRTh2 (unknown origin) stably expressed in PGD2-stimulated CHO.K1 cells preincubated for 1 hr by radio-labelled [35S]-GTPgamma...


Bioorg Med Chem Lett 24: 5111-7 (2014)


Article DOI: 10.1016/j.bmcl.2014.08.026
BindingDB Entry DOI: 10.7270/Q2N01840
More data for this
Ligand-Target Pair