BDBM50035099 3-{4-[4-(4-Fluoro-phenyl)-piperazin-1-yl]-butyl}-1H-indole::CHEMBL279586

SMILES Fc1ccc(cc1)N1CCN(CCCCc2c[nH]c3ccccc23)CC1

InChI Key InChIKey=PTKJETUJAPZSQR-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50035099   

TargetSigma non-opioid intracellular receptor 1(RAT)
H. Lundbeck

Curated by ChEMBL
LigandPNGBDBM50035099(3-{4-[4-(4-Fluoro-phenyl)-piperazin-1-yl]-butyl}-1...)
Affinity DataIC50:  5.60nMAssay Description:Binding affinity towards sigma receptor binding site 1 using [3H](+)-pentazocineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A(Rattus norvegicus (rat))
H. Lundbeck

Curated by ChEMBL
LigandPNGBDBM50035099(3-{4-[4-(4-Fluoro-phenyl)-piperazin-1-yl]-butyl}-1...)
Affinity DataIC50:  14nMAssay Description:Binding affinity towards 5-hydroxytryptamine 2A receptor binding site using [3H]ketanserin .More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
H. Lundbeck

Curated by ChEMBL
LigandPNGBDBM50035099(3-{4-[4-(4-Fluoro-phenyl)-piperazin-1-yl]-butyl}-1...)
Affinity DataIC50:  37nMAssay Description:Binding affinity towards 5-hydroxytryptamine 1A receptor binding site using [3H]8-OH-DPAT .More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
H. Lundbeck

Curated by ChEMBL
LigandPNGBDBM50035099(3-{4-[4-(4-Fluoro-phenyl)-piperazin-1-yl]-butyl}-1...)
Affinity DataIC50:  180nMAssay Description:Binding affinity towards Dopamine receptor D2 binding site using [3H]spiroperidol.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed