BDBM50035136 3H-spiro[2-benzofuran-1,4'-piperidine]::CHEMBL64369

SMILES c1ccc2c(c1)COC23CCNCC3

InChI Key InChIKey=BYOIMOJOKVUNTP-UHFFFAOYSA-N

Data  2 IC50

PDB links: 1 PDB ID matches this monomer.

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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50035136   

TargetSigma non-opioid intracellular receptor 1(Rat)
H. Lundbeck

Curated by ChEMBL
LigandPNGBDBM50035136(3H-spiro[2-benzofuran-1,4'-piperidine] | CHEMBL643...)
Affinity DataIC50: 630nMAssay Description:Compound was evaluated for the binding affinity towards Sigma receptor type 1 using radioligand ([3H]-(+)- Pentazocine) binding assay.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/29/2012
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Rat)
H. Lundbeck

Curated by ChEMBL
LigandPNGBDBM50035136(3H-spiro[2-benzofuran-1,4'-piperidine] | CHEMBL643...)
Affinity DataIC50: 1.10E+4nMAssay Description:Binding affinity towards Sigma receptor type 2 in whole rat brain homogenates except cerebellum using radioligand ([3H]DTG) binding assay.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/29/2012
Entry Details Article
PubMed