BDBM50035579 CHEMBL3356646

SMILES CC(C)(C)c1c[nH]c2cc(NC(=O)c3c[nH]c4ccccc4c3=O)ccc12

InChI Key InChIKey=WZDRQXORFYIGGS-UHFFFAOYSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50035579   

TargetCystic fibrosis transmembrane conductance regulator(Homo sapiens (Human))
Vertex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50035579(CHEMBL3356646)
Affinity DataEC50:  9nMAssay Description:Potentiation of human CFTR F508del mutant expressed in mouse NIH-3T3 cells after 30 mins by fluorescent voltage sensing optical assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCystic fibrosis transmembrane conductance regulator(Homo sapiens (Human))
Vertex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50035579(CHEMBL3356646)
Affinity DataEC50:  42nMAssay Description:Potentiation of human CFTR F508del/G551D mutant in human bronchial epithelial cells by Ussing chambers recording techniqueMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed