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BDBM50035654 CHEMBL3338441

SMILES: COC(=O)c1ncc2cc(OCc3ccccn3)ccc2c1-c1cc(OC)c(OC)c(OC)c1

InChI Key: InChIKey=SGWJKIHAJOXGJQ-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50035654   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
cGMP-specific 3',5'-cyclic phosphodiesterase


(Canis lupus familiaris)
BDBM50035654
PNG
(CHEMBL3338441)
Show SMILES COC(=O)c1ncc2cc(OCc3ccccn3)ccc2c1-c1cc(OC)c(OC)c(OC)c1
Show InChI InChI=1S/C26H24N2O6/c1-30-21-12-16(13-22(31-2)25(21)32-3)23-20-9-8-19(34-15-18-7-5-6-10-27-18)11-17(20)14-28-24(23)26(29)33-4/h5-14H,15H2,1-4H3
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MMDB

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Article
PubMed
n/an/a 34n/an/an/an/an/an/a



Mitsubishi Tanabe Pharma Corporation

Curated by ChEMBL


Assay Description
Inhibition of canine lung PDE5 using [3H]cGMP substrate by radiolabeled nucleotide method


Bioorg Med Chem Lett 24: 5175-80 (2014)


Article DOI: 10.1016/j.bmcl.2014.09.082
BindingDB Entry DOI: 10.7270/Q2F76F5Z
More data for this
Ligand-Target Pair