BDBM50035967 5-Trifluoromethyl-1-[4-(3-trifluoromethyl-phenyl)-thiazol-2-yl]-1H-pyrazole-4-carboxylic acid (3-carbamimidoyl-propyl)-amide; hydrochloride::CHEMBL557202

SMILES: NC(=N)CCCNC(=O)c1cnn(-c2nc(cs2)-c2cccc(c2)C(F)(F)F)c1C(F)(F)F

InChI Key: InChIKey=YIHPBANAYPNMTP-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50035967   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Integrin alpha-IIb/beta-3 (Homo sapiens (Human))	BDBM50035967 (5-Trifluoromethyl-1-[4-(3-trifluoromethyl-phenyl)-...) Show SMILES NC(=N)CCCNC(=O)c1cnn(-c2nc(cs2)-c2cccc(c2)C(F)(F)F)c1C(F)(F)F Show InChI InChI=1S/C19H16F6N6OS/c20-18(21,22)11-4-1-3-10(7-11)13-9-33-17(30-13)31-15(19(23,24)25)12(8-29-31)16(32)28-6-2-5-14(26)27/h1,3-4,7-9H,2,5-6H2,(H3,26,27)(H,28,32)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.30E+4	n/a	n/a	n/a	n/a	n/a	n/a
R. W. Johnson Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Inhibition of [125I]fibrinogen binding to human Fibrinogen Receptor.				J Med Chem 38: 34-41 (1995) Article DOI: 10.1021/jm00001a008 BindingDB Entry DOI: 10.7270/Q29G5NG8
					More data for this Ligand-Target Pair