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BDBM50036189 3-(Tetrahydro-furan-2-yl)-1-aza-bicyclo[2.2.2]octane::CHEMBL343182

SMILES: C1COC(C1)C1CN2CCC1CC2

InChI Key: InChIKey=NNROOISLPANLCU-UHFFFAOYNA-N

Data: 5 KI

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50036189   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Muscarinic acetylcholine receptor M2


(Homo sapiens (Human))
BDBM50036189
PNG
(3-(Tetrahydro-furan-2-yl)-1-aza-bicyclo[2.2.2]octa...)
Show SMILES C1COC(C1)C1CN2CCC1CC2
Show InChI InChI=1/C11H19NO/c1-2-11(13-7-1)10-8-12-5-3-9(10)4-6-12/h9-11H,1-8H2
PDB

UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
5.00E+3n/an/an/an/an/an/an/an/a



Uppsala University

Curated by ChEMBL


Assay Description
Binding affinity for muscarinic acetylcholine receptor M2 by measuring displacement of [3H]-QNB from guinea pig heart


J Med Chem 38: 473-87 (1995)


Article DOI: 10.1021/jm00003a011
BindingDB Entry DOI: 10.7270/Q25Q4V42
More data for this
Ligand-Target Pair
Muscarinic acetylcholine receptor M2


(Homo sapiens (Human))
BDBM50036189
PNG
(3-(Tetrahydro-furan-2-yl)-1-aza-bicyclo[2.2.2]octa...)
Show SMILES C1COC(C1)C1CN2CCC1CC2
Show InChI InChI=1/C11H19NO/c1-2-11(13-7-1)10-8-12-5-3-9(10)4-6-12/h9-11H,1-8H2
PDB

UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
5.00E+3n/an/an/an/an/an/an/an/a



Uppsala University

Curated by ChEMBL


Assay Description
Binding affinity for muscarinic acetylcholine receptor M2 by measuring displacement of [3H]-QNB from guinea pig heart


J Med Chem 38: 473-87 (1995)


Article DOI: 10.1021/jm00003a011
BindingDB Entry DOI: 10.7270/Q25Q4V42
More data for this
Ligand-Target Pair
Muscarinic acetylcholine receptor M1


(Homo sapiens (Human))
BDBM50036189
PNG
(3-(Tetrahydro-furan-2-yl)-1-aza-bicyclo[2.2.2]octa...)
Show SMILES C1COC(C1)C1CN2CCC1CC2
Show InChI InChI=1/C11H19NO/c1-2-11(13-7-1)10-8-12-5-3-9(10)4-6-12/h9-11H,1-8H2
UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
8.10E+3n/an/an/an/an/an/an/an/a



Uppsala University

Curated by ChEMBL


Assay Description
Binding affinity for muscarinic acetylcholine receptor M1 by measuring displacement of [3H]-QNB from guinea pig cerebral cortex


J Med Chem 38: 473-87 (1995)


Article DOI: 10.1021/jm00003a011
BindingDB Entry DOI: 10.7270/Q25Q4V42
More data for this
Ligand-Target Pair
Muscarinic acetylcholine receptor M1


(Homo sapiens (Human))
BDBM50036189
PNG
(3-(Tetrahydro-furan-2-yl)-1-aza-bicyclo[2.2.2]octa...)
Show SMILES C1COC(C1)C1CN2CCC1CC2
Show InChI InChI=1/C11H19NO/c1-2-11(13-7-1)10-8-12-5-3-9(10)4-6-12/h9-11H,1-8H2
UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
8.10E+3n/an/an/an/an/an/an/an/a



Uppsala University

Curated by ChEMBL


Assay Description
Binding affinity for muscarinic acetylcholine receptor M1 by measuring displacement of [3H]-QNB from guinea pig cerebral cortex


J Med Chem 38: 473-87 (1995)


Article DOI: 10.1021/jm00003a011
BindingDB Entry DOI: 10.7270/Q25Q4V42
More data for this
Ligand-Target Pair
Muscarinic acetylcholine receptor M3


(Cavia porcellus)
BDBM50036189
PNG
(3-(Tetrahydro-furan-2-yl)-1-aza-bicyclo[2.2.2]octa...)
Show SMILES C1COC(C1)C1CN2CCC1CC2
Show InChI InChI=1/C11H19NO/c1-2-11(13-7-1)10-8-12-5-3-9(10)4-6-12/h9-11H,1-8H2
MMDB

Reactome pathway
KEGG

UniProtKB/TrEMBL

B.MOAD
DrugBank
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
1.30E+4n/an/an/an/an/an/an/an/a



Uppsala University

Curated by ChEMBL


Assay Description
Binding affinity for muscarinic acetylcholine receptor M3 by measuring displacement of [3H]-QNB from guinea pig parotid gland


J Med Chem 38: 473-87 (1995)


Article DOI: 10.1021/jm00003a011
BindingDB Entry DOI: 10.7270/Q25Q4V42
More data for this
Ligand-Target Pair