BDBM50036682 CHEMBL120719::[5-(2,2-Dicyano-vinyl)-2-hydroxy-3-methoxy-benzylsulfanyl]-acetic acid

SMILES [#6]-[#8]-c1cc(\[#6]=[#6](/C#N)C#N)cc(-[#6]-[#16]-[#6]-[#6](-[#8])=O)c1-[#8]

InChI Key InChIKey=VUUXIIIZODMBCO-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50036682   

TargetEpidermal growth factor receptor(Homo sapiens (Human))
Hebrew University Of Jerusalem

Curated by ChEMBL
LigandPNGBDBM50036682(CHEMBL120719 | [5-(2,2-Dicyano-vinyl)-2-hydroxy-3-...)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of HER-14 (human EGFR overexpressing NIH3T3) cell proliferationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Hebrew University Of Jerusalem

Curated by ChEMBL
LigandPNGBDBM50036682(CHEMBL120719 | [5-(2,2-Dicyano-vinyl)-2-hydroxy-3-...)
Affinity DataIC50:  5.40E+4nMAssay Description:Inhibition of HER-14 (human EGFR overexpressing NIH3T3) cell proliferationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Hebrew University Of Jerusalem

Curated by ChEMBL
LigandPNGBDBM50036682(CHEMBL120719 | [5-(2,2-Dicyano-vinyl)-2-hydroxy-3-...)
Affinity DataIC50:  9.60E+4nMAssay Description:Inhibitiory concentration against EGF receptor by polyGAT phosphorylationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor/Receptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Hebrew University Of Jerusalem

Curated by ChEMBL
LigandPNGBDBM50036682(CHEMBL120719 | [5-(2,2-Dicyano-vinyl)-2-hydroxy-3-...)
Affinity DataIC50:  9.10E+4nMAssay Description:Inhibition of HER-14 (human EGFR overexpressing NIH3T3) cell proliferationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed