BDBM50036756 1'-phenethylspiro[1,2,3,4-tetrahydronaphthalene-2,4'-(hexahydropyridine)]-1-ol; hydrochloride::CHEMBL146144::CHEMBL542942

SMILES OC1c2ccccc2CCC11CCN(CCc2ccccc2)CC1

InChI Key InChIKey=XKIGTQXAOLOQJD-UHFFFAOYSA-N

Data  8 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50036756   

Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
Merck Sharp And Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50036756(1'-phenethylspiro[1,2,3,4-tetrahydronaphthalene-2,...)
Affinity DataKi:  0.400nMAssay Description:Binding affinity for displacement of [3H]ketanserin to human 5-hydroxytryptamine 2A receptor stably expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A(Rattus norvegicus (rat))
Merck Sharp And Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50036756(1'-phenethylspiro[1,2,3,4-tetrahydronaphthalene-2,...)
Affinity DataKi:  0.590nMAssay Description:Binding affinity for displacement of [3H]ketanserin to rat 5-hydroxytryptamine 2A receptor stably expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50036756(1'-phenethylspiro[1,2,3,4-tetrahydronaphthalene-2,...)
Affinity DataKi:  4.40nMAssay Description:Binding affinity for sigma receptor of guinea pig whole brain using [3H]-SKF- 100047 radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2C(Homo sapiens (Human))
Merck Sharp And Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50036756(1'-phenethylspiro[1,2,3,4-tetrahydronaphthalene-2,...)
Affinity DataKi:  230nMAssay Description:Binding affinity for displacement of [3H]mesulergine to human 5-hydroxytryptamine 2C receptor stably expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Merck Sharp And Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50036756(1'-phenethylspiro[1,2,3,4-tetrahydronaphthalene-2,...)
Affinity DataKi:  1.20E+3nMAssay Description:Displacement of [3H]-dofetilide to HEK cells stably expressing hERG voltage-gated IKr potassium channel Kv11.1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Merck Sharp And Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50036756(1'-phenethylspiro[1,2,3,4-tetrahydronaphthalene-2,...)
Affinity DataKi:  1.20E+3nMAssay Description:Inhibition of human ERG channelMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Merck Sharp And Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50036756(1'-phenethylspiro[1,2,3,4-tetrahydronaphthalene-2,...)
Affinity DataKi:  1.70E+3nMAssay Description:Binding affinity for displacement of [3H]spiperone to human dopamine D2 (hD2) receptors stably expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Merck Sharp And Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50036756(1'-phenethylspiro[1,2,3,4-tetrahydronaphthalene-2,...)
Affinity DataKi: >1.00E+4nMAssay Description:Binding affinity for dopamine D2 receptor using [3H]spiperone in guinea pig striatumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed