BDBM50036859 CHEMBL300735::N-{4-[(5-Methoxy-chroman-3-yl)-propyl-amino]-butyl}-4-methyl-benzenesulfonamide; compound with oxalic acid

SMILES CCCN(CCCCNS(=O)(=O)c1ccc(C)cc1)C1COc2cccc(OC)c2C1

InChI Key InChIKey=GCJDLTIMRVUXDP-UHFFFAOYSA-N

Data  1 KI  14 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 15 hits for monomerid = 50036859   

Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Universit£

Curated by ChEMBL
LigandPNGBDBM50036859(CHEMBL300735 | N-{4-[(5-Methoxy-chroman-3-yl)-prop...)
Affinity DataKi:  1nMAssay Description:Binding affinity of a compound to rat brain 5-hydroxytryptamine 1A (serotonin) receptor assayed by radiolabeled [3H]-8-OH-DPAT ligand displacementMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-2A adrenergic receptor(BOVINE)
Universit£

Curated by ChEMBL
LigandPNGBDBM50036859(CHEMBL300735 | N-{4-[(5-Methoxy-chroman-3-yl)-prop...)
Affinity DataIC50:  2.00E+3nMAssay Description:Binding affinity against alpha-2 adrenergic receptor in calf frontal cortexMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Universit£

Curated by ChEMBL
LigandPNGBDBM50036859(CHEMBL300735 | N-{4-[(5-Methoxy-chroman-3-yl)-prop...)
Affinity DataIC50:  20nMAssay Description:Binding affinity against 5-hydroxytryptamine 1A (5-HT1A) receptor in rat hippocampus membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1B(Rattus norvegicus (Rat))
Universit£

Curated by ChEMBL
LigandPNGBDBM50036859(CHEMBL300735 | N-{4-[(5-Methoxy-chroman-3-yl)-prop...)
Affinity DataIC50:  9.00E+3nMAssay Description:Binding affinity for 5-hydroxytryptamine 1B receptor in rat cortex, striatum and globus pallidusMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(1A) dopamine receptor(BOVINE)
Universit£

Curated by ChEMBL
LigandPNGBDBM50036859(CHEMBL300735 | N-{4-[(5-Methoxy-chroman-3-yl)-prop...)
Affinity DataIC50:  2.00E+4nMAssay Description:Binding affinity towards dopamine receptor D1 in calf striatumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(BOVINE)
Universit£

Curated by ChEMBL
LigandPNGBDBM50036859(CHEMBL300735 | N-{4-[(5-Methoxy-chroman-3-yl)-prop...)
Affinity DataIC50:  100nMAssay Description:Binding affinity against D2 receptor in calf caudate nucleusMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1A adrenergic receptor(CALF)
Universit£

Curated by ChEMBL
LigandPNGBDBM50036859(CHEMBL300735 | N-{4-[(5-Methoxy-chroman-3-yl)-prop...)
Affinity DataIC50:  3.00E+3nMAssay Description:Binding affinity against alpha-1 adrenergic receptor in calf frontal cortexMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(1A) dopamine receptor(BOVINE)
Universit£

Curated by ChEMBL
LigandPNGBDBM50036859(CHEMBL300735 | N-{4-[(5-Methoxy-chroman-3-yl)-prop...)
Affinity DataIC50:  2.00E+4nMAssay Description:Binding affinity towards dopamine receptor D1 in calf striatumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1B(Rattus norvegicus (Rat))
Universit£

Curated by ChEMBL
LigandPNGBDBM50036859(CHEMBL300735 | N-{4-[(5-Methoxy-chroman-3-yl)-prop...)
Affinity DataIC50:  2.00E+4nMAssay Description:Binding affinity for 5-hydroxytryptamine 1B receptor in rat cortex, striatum and globus pallidusMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Universit£

Curated by ChEMBL
LigandPNGBDBM50036859(CHEMBL300735 | N-{4-[(5-Methoxy-chroman-3-yl)-prop...)
Affinity DataIC50:  0.700nMAssay Description:Binding affinity against 5-hydroxytryptamine 1A (5-HT1A) receptor in rat hippocampus membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(BOVINE)
Universit£

Curated by ChEMBL
LigandPNGBDBM50036859(CHEMBL300735 | N-{4-[(5-Methoxy-chroman-3-yl)-prop...)
Affinity DataIC50:  60nMAssay Description:Binding affinity against D2 receptor in calf caudate nucleusMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A(BOVINE)
Universit£

Curated by ChEMBL
LigandPNGBDBM50036859(CHEMBL300735 | N-{4-[(5-Methoxy-chroman-3-yl)-prop...)
Affinity DataIC50:  8.00E+3nMAssay Description:Binding affinity towards 5-hydroxytryptamine 2 receptor in calf frontal cortexMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-2A adrenergic receptor(BOVINE)
Universit£

Curated by ChEMBL
LigandPNGBDBM50036859(CHEMBL300735 | N-{4-[(5-Methoxy-chroman-3-yl)-prop...)
Affinity DataIC50:  2.00E+3nMAssay Description:Binding affinity against alpha-2 adrenergic receptor in calf frontal cortexMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A(BOVINE)
Universit£

Curated by ChEMBL
LigandPNGBDBM50036859(CHEMBL300735 | N-{4-[(5-Methoxy-chroman-3-yl)-prop...)
Affinity DataIC50:  8.00E+3nMAssay Description:Binding affinity towards 5-hydroxytryptamine 2 receptor in calf frontal cortexMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1A adrenergic receptor(CALF)
Universit£

Curated by ChEMBL
LigandPNGBDBM50036859(CHEMBL300735 | N-{4-[(5-Methoxy-chroman-3-yl)-prop...)
Affinity DataIC50:  3.00E+3nMAssay Description:Binding affinity against alpha-1 adrenergic receptor in calf frontal cortexMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed