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BDBM50036913 (+-)-4-(alpha,2,3-trimethylbenzyl)imidazole::4-[1-(2,3-dimethylphenyl)ethyl]-1H-imidazole::CHEMBL77921::medetomidine

SMILES: CC(c1cnc[nH]1)c1cccc(C)c1C

InChI Key: InChIKey=CUHVIMMYOGQXCV-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50036913   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Alpha-2A adrenergic receptor


(Homo sapiens (Human))
BDBM50036913
PNG
((+-)-4-(alpha,2,3-trimethylbenzyl)imidazole | 4-[1...)
Show SMILES CC(c1cnc[nH]1)c1cccc(C)c1C
Show InChI InChI=1S/C13H16N2/c1-9-5-4-6-12(10(9)2)11(3)13-7-14-8-15-13/h4-8,11H,1-3H3,(H,14,15)
UniProtKB/SwissProt

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PC cid
PC sid
UniChem

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Article
PubMed
n/an/a 3.40E+3n/an/an/an/an/an/a



Ohio State University

Curated by ChEMBL


Assay Description
Tested for its ability to antagonize epinephrine induced primary wave aggregation in human platelets at alpha-2A-adrenergic receptor sites.


J Med Chem 37: 2328-33 (1994)


Article DOI: 10.1021/jm00041a011
BindingDB Entry DOI: 10.7270/Q26110ZR
More data for this
Ligand-Target Pair