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BDBM50037027 CHEMBL3355276

SMILES: [#6]\[#6](-[#6])=[#6]\[#6]-[#6]\[#6](-[#6])=[#6]\[#6]-[#8]-[#6](=O)-c1cccc(-[#6])c1

InChI Key: InChIKey=BDORWRKNGCXKSQ-RVDMUPIBSA-N

Data: 3 IC50  1 EC50

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50037027   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Transient receptor potential cation channel subfamily A member 1


(Rattus norvegicus)
BDBM50037027
PNG
(CHEMBL3355276)
Show SMILES CC(C)=CCC\C(C)=C\COC(=O)c1cccc(C)c1
Show InChI InChI=1S/C18H24O2/c1-14(2)7-5-8-15(3)11-12-20-18(19)17-10-6-9-16(4)13-17/h6-7,9-11,13H,5,8,12H2,1-4H3/b15-11+
KEGG

UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/an/a 2.40E+3n/an/an/an/a



Sapienza University of Rome

Curated by ChEMBL


Assay Description
Agonist activity at rat TRPA1 expressed in HEK293 cells assessed as increase in intracellular Ca2+ concentration by Fluo-4-AM dye based spectrofluori...


Bioorg Med Chem Lett 24: 5507-11 (2015)


Article DOI: 10.1016/j.bmcl.2014.10.012
BindingDB Entry DOI: 10.7270/Q2SB47B3
More data for this
Ligand-Target Pair
Transient receptor potential cation channel subfamily V member 1


(Homo sapiens (Human))
BDBM50037027
PNG
(CHEMBL3355276)
Show SMILES CC(C)=CCC\C(C)=C\COC(=O)c1cccc(C)c1
Show InChI InChI=1S/C18H24O2/c1-14(2)7-5-8-15(3)11-12-20-18(19)17-10-6-9-16(4)13-17/h6-7,9-11,13H,5,8,12H2,1-4H3/b15-11+
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a>1.00E+5n/an/an/an/an/an/a



Sapienza University of Rome

Curated by ChEMBL


Assay Description
Antagonist activity against human TRPV1 expressed in HEK293 cells assessed as inhibition of capsaicin-induced increase in intracellular Ca2+ concentr...


Bioorg Med Chem Lett 24: 5507-11 (2015)


Article DOI: 10.1016/j.bmcl.2014.10.012
BindingDB Entry DOI: 10.7270/Q2SB47B3
More data for this
Ligand-Target Pair
Transient receptor potential M8 protein (TRPM8)


(Rattus norvegicus (Rat))
BDBM50037027
PNG
(CHEMBL3355276)
Show SMILES CC(C)=CCC\C(C)=C\COC(=O)c1cccc(C)c1
Show InChI InChI=1S/C18H24O2/c1-14(2)7-5-8-15(3)11-12-20-18(19)17-10-6-9-16(4)13-17/h6-7,9-11,13H,5,8,12H2,1-4H3/b15-11+
UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a>1.00E+5n/an/an/an/an/an/a



Sapienza University of Rome

Curated by ChEMBL


Assay Description
Antagonist activity against rat TRPM8 expressed in HEK293 cells assessed as inhibition of icilin-induced increase in intracellular Ca2+ concentration...


Bioorg Med Chem Lett 24: 5507-11 (2015)


Article DOI: 10.1016/j.bmcl.2014.10.012
BindingDB Entry DOI: 10.7270/Q2SB47B3
More data for this
Ligand-Target Pair
Transient receptor potential cation channel subfamily A member 1


(Rattus norvegicus)
BDBM50037027
PNG
(CHEMBL3355276)
Show SMILES CC(C)=CCC\C(C)=C\COC(=O)c1cccc(C)c1
Show InChI InChI=1S/C18H24O2/c1-14(2)7-5-8-15(3)11-12-20-18(19)17-10-6-9-16(4)13-17/h6-7,9-11,13H,5,8,12H2,1-4H3/b15-11+
KEGG

UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 1.40E+3n/an/an/an/an/an/a



Sapienza University of Rome

Curated by ChEMBL


Assay Description
Antagonist activity against rat TRPA1 expressed in HEK293 cells assessed as inhibition of AITC-induced increase in intracellular Ca2+ concentration b...


Bioorg Med Chem Lett 24: 5507-11 (2015)


Article DOI: 10.1016/j.bmcl.2014.10.012
BindingDB Entry DOI: 10.7270/Q2SB47B3
More data for this
Ligand-Target Pair