BDBM50037396 8-Amino-2-(4-amino-phenyl)-5-methoxy-chromen-4-one::CHEMBL115397

SMILES COc1ccc(N)c2oc(cc(=O)c12)-c1ccc(N)cc1

InChI Key InChIKey=VORQZXYMFOGDAI-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50037396   

TargetProto-oncogene tyrosine-protein kinase Src(Human)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50037396(8-Amino-2-(4-amino-phenyl)-5-methoxy-chromen-4-one...)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of in vitro protein-tyrosine kinase activity of p60v-src enzyme in presence of 5 uM ATP.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50037396(8-Amino-2-(4-amino-phenyl)-5-methoxy-chromen-4-one...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of in vitro activity of EGFr enzyme from A431 cells in presence of 5 uM ATPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTyrosine-protein kinase Lck(Human)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50037396(8-Amino-2-(4-amino-phenyl)-5-methoxy-chromen-4-one...)
Affinity DataIC50: 1.62E+6nMAssay Description:In vitro inhibition of protein-tyrosine activity of p56lck enzyme in presence of 50 uM ATPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed