BDBM50037413 6-Amino-2-(4-amino-phenyl)-chromen-4-one::CHEMBL112925

SMILES Nc1ccc(cc1)-c1cc(=O)c2cc(N)ccc2o1

InChI Key InChIKey=FUTDIJXBLRBDGJ-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50037413   

TargetEpidermal growth factor receptor(Homo sapiens (Human))
Purdue University

Curated by ChEMBL
LigandPNGBDBM50037413(6-Amino-2-(4-amino-phenyl)-chromen-4-one | CHEMBL1...)
Affinity DataIC50:  8.70E+3nMAssay Description:Inhibition of in vitro activity of EGFr enzyme from A431 cells in presence of 5 uM ATPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Purdue University

Curated by ChEMBL
LigandPNGBDBM50037413(6-Amino-2-(4-amino-phenyl)-chromen-4-one | CHEMBL1...)
Affinity DataIC50:  2.88E+4nMAssay Description:Inhibition of in vitro protein-tyrosine kinase activity of p60v-src enzyme in presence of 5 uM ATP.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Lck(Homo sapiens (Human))
Purdue University

Curated by ChEMBL
LigandPNGBDBM50037413(6-Amino-2-(4-amino-phenyl)-chromen-4-one | CHEMBL1...)
Affinity DataIC50:  1.03E+5nMAssay Description:In vitro inhibition of protein-tyrosine activity of p56lck enzyme in presence of 50 uM ATPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed